Artigo Revisado por pares

Ultrasonic nebulisation of pentamidine isethionate

1993; Elsevier BV; Volume: 98; Issue: 1-3 Linguagem: Inglês

10.1016/0378-5173(93)90039-i

ISSN

1873-3476

Autores

Kevin Taylor, C. Hoare,

Tópico(s)

Innovative Microfluidic and Catalytic Techniques Innovation

Resumo

The properties of pentamidine isethionate aerosols produced by an ultrasonic nebuliser frequently used in clinical practice have been investigated. The mass median diameter of the aerosols was initially 5.1−5.6 μm, depending on the volume of solution atomized and the output setting of the nebuliser. The aerosol size tended to decrease, and the solution temperature increase with time. Between 57 and 74% of drug placed in the nebuliser was delivered during use, the remainder being associated with the device.

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