Arterial thrombosis in four patients treated with thalidomide
2004; Taylor & Francis; Volume: 46; Issue: 2 Linguagem: Inglês
10.1080/10428190400015675
ISSN1042-8194
AutoresSarah L Scarpace, Theresa Hahn, Hilary N. Roy, Karen Brown, Pamela Paplham, Asher Chanan‐Khan, Koen van Besien, Philip McCarthy,
Tópico(s)Systemic Lupus Erythematosus Research
ResumoThalidomide has been associated with venous thrombotic events, as reported in the post-marketing surveillance reports by Celgene Corporation; as well as case reports in the literature. Seven arterial thrombotic events have been reported in patients receiving thalidomide with 3 cases occurring in patients with other predisposing conditions. We report 4 additional cases of arterial thromboses in 1 lymphoma and 3 myeloma patients treated with thalidomide. The mechanism for these events is unclear; however, it is significant that 2 patients were receiving concomitant anticoagulation with aspirin and warfarin.
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