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Association between Tumor Angiogenesis and Borrmann Type 4 Carcinomas of the Stomach

1998; Karger Publishers; Volume: 55; Issue: 5 Linguagem: Inglês

10.1159/000011896

1423-0232

Nobuhiko Tanigawa, Hirokazu Amaya, Mitsuyoshi Matsumura, Caide Lu, Masayuki Iki,

Esophageal Cancer Research and Treatment

A total of 202 gastric carcinomas, including 33 type 4 carcinomas, were studied. Intratumoral vessels were stained with an anti-CD34 monoclonal antibody before being quantitated by light microscopy (x200). The mean vessel counts for type 4 carcinomas were significantly higher than those for any other type of carcinoma, with the exception of type 1 carcinomas. Multivariate logistic regression showed that the vessel count was one of independent variables associated with type 4 carcinomas. In addition, survival analysis demonstrated that patients with type 4 carcinoma had significantly less favorable survival rates than those with other types of carcinomas.