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One-year survival in patients with acute myocardial infarction and a saphenous vein graft culprit treated with primary angioplasty

2003; Elsevier BV; Volume: 91; Issue: 10 Linguagem: Inglês

10.1016/s0002-9149(03)00277-7

1879-1913

Thanh T. Nguyen, William W. O’Neill, Cindy L. Grines, Gregg W. Stone, Bruce R. Brodie, David A. Cox, Lorelei Grines, Judith Boura, Simon Dixon,

Cardiac Imaging and Diagnostics

Among patients with acute myocardial infarction (AMI), those with prior coronary artery bypass grafting (CABG) represent a high-risk group for early and late clinical events. 1 Fibrinolytic Therapy Trialists (FTT) Collaborative GroupIndications for fibrinolytic therapy in suspected acute myocardial infarction collaborative overview of early mortality and major morbidity results from all randomized trials of more than 1000 patients. Lancet. 1994; 343: 311-322 PubMed Google Scholar , 2 Lee K.L. Woodlief L.H. Topol E.J. Weaver W.D. Betriu A. Col J. Simoons M. Aylward P. van de Werf F. Califf R.M. GUSTO-I InvestigatorsPredictors of 30-day mortality in the era of reperfusion for acute myocardial infarction. Results from an international trial of 41,021 patients. Circulation. 1995; 91: 1659-1668 Crossref PubMed Scopus (991) Google Scholar , 3 Peterson L.R. Chandra N.C. French W.J. Rodgers W.J. Weaver W.D. Tiefenbrunn A.J. National Registry of Myocardial Infarction-2 InvestigatorsReperfusion therapy in patients with acute myocardial infarction and prior coronary artery bypass graft surgery (National Registry of Myocardial Infarction-2). Am J Cardiol. 1999; 84: 1287-1291 Abstract Full Text Full Text PDF PubMed Scopus (26) Google Scholar , 4 Stone G.W. Grines C.L. Browne K.F. Marco J. Rothbaum D. O'Keefe J. Hartzler G.O. Overlie P. Donohue B. Chelliah N. et al. Predictors of in-hospital and 6-month outcome after acute myocardial infarction in the reperfusion era the Primary Angioplasty in Myocardial Infarction (PAMI) trial. J Am Coll Cardiol. 1995; 25: 370-377 Abstract Full Text PDF PubMed Scopus (293) Google Scholar , 5 Stone G.W. Brodie B.R. Griffin J.J. Grines L. Boura J. O'Neill W.W. Grines C.L. Second Primary Angioplasty in Myocardial Infarction Trial (PAMI-2) InvestigatorsClinical and angiographic outcomes in patients with previous coronary artery bypass graft surgery treated with primary balloon angioplasty for acute myocardial infarction. J Am Coll Cardiol. 2000; 35: 605-611 Abstract Full Text Full Text PDF PubMed Scopus (75) Google Scholar Previous studies have identified prior CABG as an independent predictor of mortality. 2 Lee K.L. Woodlief L.H. Topol E.J. Weaver W.D. Betriu A. Col J. Simoons M. Aylward P. van de Werf F. Califf R.M. GUSTO-I InvestigatorsPredictors of 30-day mortality in the era of reperfusion for acute myocardial infarction. Results from an international trial of 41,021 patients. Circulation. 1995; 91: 1659-1668 Crossref PubMed Scopus (991) Google Scholar , 3 Peterson L.R. Chandra N.C. French W.J. Rodgers W.J. Weaver W.D. Tiefenbrunn A.J. National Registry of Myocardial Infarction-2 InvestigatorsReperfusion therapy in patients with acute myocardial infarction and prior coronary artery bypass graft surgery (National Registry of Myocardial Infarction-2). Am J Cardiol. 1999; 84: 1287-1291 Abstract Full Text Full Text PDF PubMed Scopus (26) Google Scholar Mechanisms contributing to the poor survival of patients with post-CABG AMI have not been well defined, although it appears this is partly related to a higher baseline clinical risk profile, as well as the type of infarct vessel. 5 Stone G.W. Brodie B.R. Griffin J.J. Grines L. Boura J. O'Neill W.W. Grines C.L. Second Primary Angioplasty in Myocardial Infarction Trial (PAMI-2) InvestigatorsClinical and angiographic outcomes in patients with previous coronary artery bypass graft surgery treated with primary balloon angioplasty for acute myocardial infarction. J Am Coll Cardiol. 2000; 35: 605-611 Abstract Full Text Full Text PDF PubMed Scopus (75) Google Scholar , 6 Labinaz M. Sketch M.H. Ellis S.G. Abramowitz B.M. Stebbins A.L. Pieper K.S. Holmes D.R. Califf R.M. Topol E.J. Global Utilization of Streptokinase and Tissue Plasminogen Activator for Occluded Coronary Arteries trial (GUSTO-I)Outcome of acute ST-segment elevation myocardial infarction in patients with prior coronary artery bypass surgery receiving thrombolytic therapy. Am Heart J. 2001; 141: 469-477 Abstract Full Text Full Text PDF PubMed Scopus (40) Google Scholar Recent data from Suwaidi et al 7 Suwaidi J.A. Velianou J.L. Berger P.B. Mathew V. Garratt K.N. Reeder G.S. Grill D.E. Holmes D.R. Primary percutaneous coronary interventions in patients with acute myocardial infarction and prior coronary artery bypass grafting. Am Heart J. 2001; 142: 452-459 Abstract Full Text Full Text PDF PubMed Scopus (49) Google Scholar suggest that treatment of a saphenous vein graft (SVG) is a more important predictor of outcome than a history of CABG. 7 Suwaidi J.A. Velianou J.L. Berger P.B. Mathew V. Garratt K.N. Reeder G.S. Grill D.E. Holmes D.R. Primary percutaneous coronary interventions in patients with acute myocardial infarction and prior coronary artery bypass grafting. Am Heart J. 2001; 142: 452-459 Abstract Full Text Full Text PDF PubMed Scopus (49) Google Scholar In a previous report from the Second Primary Angioplasty in Myocardial Infarction (PAMI-2) trial, we found that patients with acute occlusion of an SVG were less likely to achieve Thrombolysis In Myocardial Infarction (TIMI) grade 3 flow after primary angioplasty than those with a native vessel culprit. 5 Stone G.W. Brodie B.R. Griffin J.J. Grines L. Boura J. O'Neill W.W. Grines C.L. Second Primary Angioplasty in Myocardial Infarction Trial (PAMI-2) InvestigatorsClinical and angiographic outcomes in patients with previous coronary artery bypass graft surgery treated with primary balloon angioplasty for acute myocardial infarction. J Am Coll Cardiol. 2000; 35: 605-611 Abstract Full Text Full Text PDF PubMed Scopus (75) Google Scholar Based on these observations, we sought to examine factors contributing to the poor survival of patients with AMI who had acute occlusion of a SVG, and hypothesized that this may be related to suboptimal flow restoration in the infarct artery after mechanical reperfusion.