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Artigo Produção Nacional Revisado por pares
BIBTEX RIS

Tonic serotonergic control of ingestive behaviours in the pigeon (Columba livia): The role of the arcopallium

2009; Elsevier BV; Volume: 205; Issue: 2 Linguagem: Inglês

10.1016/j.bbr.2009.07.017

ISSN

1872-7549

Autores

Luciane Coutinho Azevedo Campanella, Amanda Alcaraz da Silva, Dayane Stephany Gellert, Caroline Parreira, Mayara Caldas Ramos, Marta Aparecida Paschoalini, José Marino–Neto,

Tópico(s)

Primate Behavior and Ecology

Resumo

This study examined the acute changes in feeding and drinking behaviours of free-feeding and free-drinking pigeons, in response to local injections of metergoline (MET, 5-HT1/2 receptor antagonist; 7 and 20 nmol), GR46611 (GR, 5-HT1B/1D agonist; 2 and 6 nmol) or vehicle, into two components of the arcopallium: the nucleus taeniae of the amygdala (TnA) and the arcopallium intermedium (AI). In the TnA, the highest MET dose elicited a short-lived hyperphagy, without affecting drinking or non-ingestive behaviours during the first hour after injection. In contrast, all MET doses promptly increased drinking when injected in the AI, without affecting feeding; this effect was still evident 3 and 24 h after the treatment. When injected in the TnA, the highest GR dose promptly increased both food and water intake; these effects persisted 24 h after the treatments. GR injections in the AI evoked long-lasting increases in drinking, but not in feeding. Injections of these drugs into other arcopallial nuclei evoked no significant ingestive effects. These data indicate the presence of a tonic inhibitory influence of serotonergic inputs, partially mediated by 5-HT1B/1D receptors, on feeding- and drinking-related TnA circuits and on mechanisms controlling drinking in the AI. Compared to data from the rodent medial amygdala, our results suggest that a tonic inhibitory 5-HTergic control of feeding (but not drinking) behaviour, mediated by 5-HT1/2 receptors and exerted in the medial amygdaloid area, may represent a broadly conserved functional attribute in the amniote brain, but probably involves many important taxa-specific neural mechanisms.

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