Palladium-Catalyzed Carboauration of Alkynes and Palladium/Gold Cross-Coupling
2009; American Chemical Society; Volume: 28; Issue: 5 Linguagem: Inglês
10.1021/om801206g
ISSN1520-6041
AutoresYili Shi, Stephen D. Ramgren, Suzanne A. Blum,
Tópico(s)Catalytic C–H Functionalization Methods
ResumoA new palladium-catalyzed syn carboauration of alkynes proceeds in 2 h at ambient temperature with complete regioselectivity. The resulting α-ester vinyl−gold intermediates are resistant to rapid protodemetalation, permitting their participation in new one-pot palladium-and-gold cross-coupling reactions and electrophilic trapping reactions.
Referência(s)