Birth weight at high altitudes in Peru
2006; Elsevier BV; Volume: 93; Issue: 3 Linguagem: Inglês
10.1016/j.ijgo.2006.02.023
ISSN1879-3479
AutoresStella M. Hartinger, Vilma Tapia, Carlos Carrillo, Lidia Bejarano Bejarano, Gustavo F. Gonzáles,
Tópico(s)High Altitude and Hypoxia
ResumoInternational Journal of Gynecology & ObstetricsVolume 93, Issue 3 p. 275-281 Special articles Birth weight at high altitudes in Peru S. Hartinger, S. Hartinger Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Peru Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, PeruSearch for more papers by this authorV. Tapia, V. Tapia Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, PeruSearch for more papers by this authorC. Carrillo, C. Carrillo Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, PeruSearch for more papers by this authorL. Bejarano, L. Bejarano Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, PeruSearch for more papers by this authorG.F. Gonzales, Corresponding Author G.F. Gonzales iiad@upch.edu.pe Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Peru Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, PeruCorresponding author. Av. Honorio Delgado 430, Urb. Ingenieria, Lima 31, Peru.Search for more papers by this author S. Hartinger, S. Hartinger Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Peru Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, PeruSearch for more papers by this authorV. Tapia, V. Tapia Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, PeruSearch for more papers by this authorC. Carrillo, C. Carrillo Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, PeruSearch for more papers by this authorL. Bejarano, L. Bejarano Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, PeruSearch for more papers by this authorG.F. Gonzales, Corresponding Author G.F. Gonzales iiad@upch.edu.pe Department of Biological and Physiological Sciences, Faculty of Sciences and Philosophy, Universidad Peruana Cayetano Heredia, Peru Instituto de Investigaciones de la Altura, Universidad Peruana Cayetano Heredia, PeruCorresponding author. Av. Honorio Delgado 430, Urb. Ingenieria, Lima 31, Peru.Search for more papers by this author First published: 06 May 2006 https://doi.org/10.1016/j.ijgo.2006.02.023Citations: 34Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinked InRedditWechat Abstract Objective: To determine whether birth weights are lower at high altitudes, and whether gestational age at birth and a population's length of residence mitigate the effect of high altitude. Methods: The birth weights of 84,173 neonates recorded in the Peruvian Perinatal Information System Database were analyzed between 1995 and 2002 for the cities of Lima (150 m), Huancayo (3280 m), Cuzco (3400 m), and Juliaca (3800 m). Results: Birth weight was lower at high altitude, but there was no linear relation between altitude of residence and birth weight. Mean birth weight was higher in Juliaca than in Huancayo. There were no significant differences between the 4 cities regarding birth weights of infants born between 28 and 35 weeks of gestation. However, for infants born between 36 and 42 weeks, birth weight was lower at higher altitudes. This may be due to inadequate maternal oxygenation later in pregnancy at high altitude. In the multivariate analysis, after controlling for maternal age, marital status, parity, body mass index, pre-eclampsia or hemorrhage during pregnancy, and education, as well as sex of the newborn and gestational age at birth, birth weight was lower in all cities located at a higher altitude than Lima. Yet, longer residence at high altitudes may play a protective role. Juliaca (3800 m), where the population has resided the longest, had the lowest reduction in birth weight compared with Lima (150 m); Cuzco had intermediate values; and Huancayo (3280 m), where the population has resided the shortest, had the highest reduction in birth weight. Conclusions: Birth weight reduction, which is independent of socioeconomic factors, occurs only in births at term and may be less severe in populations that have resided longer at high altitudes. Citing Literature Volume93, Issue3June 2006Pages 275-281 RelatedInformation
Referência(s)