Artigo Acesso aberto Revisado por pares

An indolent type of Epstein-Barr virus-associated T-cell-rich B-cell lymphoma of the skin: Report of a case

1996; Wiley; Volume: 52; Issue: 3 Linguagem: Inglês

10.1002/(sici)1096-8652(199607)52

ISSN

1096-8652

Autores

Hitoshi Take, Kazuo Kubota, Toshio Fukuda, Shogo Shinonome, Osamu Ishikawa, Takuo Shirakura,

Tópico(s)

Lymphoma Diagnosis and Treatment

Resumo

American Journal of HematologyVolume 52, Issue 3 p. 221-223 Brief ReportFree Access An indolent type of Epstein-Barr virus-associated T-cell-rich B-cell lymphoma of the skin: Report of a case Hitoshi Take, Corresponding Author Hitoshi Take Department of Medicine, Kusatsu Branch Hospital, Gunma University School of Medicine, Gunma, JapanDepartment of Medicine, Kusatsu Branch Hospital, Gunma University School of Medicine, Kusatsu, Gunma 377-17, JapanSearch for more papers by this authorKazuo Kubota, Kazuo Kubota Department of Medicine, Kusatsu Branch Hospital, Gunma University School of Medicine, Gunma, JapanSearch for more papers by this authorToshio Fukuda, Toshio Fukuda Second Department of Pathology, Gunma University School of Medicine, Gunma, JapanSearch for more papers by this authorShogo Shinonome, Shogo Shinonome Third Department of Internal Medicine, Gunma University School of Medicine, Gunma, JapanSearch for more papers by this authorOsamu Ishikawa, Osamu Ishikawa Department of Dermatology, Gunma University School of Medicine, Gunma, JapanSearch for more papers by this authorTakuo Shirakura, Takuo Shirakura Department of Medicine, Kusatsu Branch Hospital, Gunma University School of Medicine, Gunma, JapanSearch for more papers by this author Hitoshi Take, Corresponding Author Hitoshi Take Department of Medicine, Kusatsu Branch Hospital, Gunma University School of Medicine, Gunma, JapanDepartment of Medicine, Kusatsu Branch Hospital, Gunma University School of Medicine, Kusatsu, Gunma 377-17, JapanSearch for more papers by this authorKazuo Kubota, Kazuo Kubota Department of Medicine, Kusatsu Branch Hospital, Gunma University School of Medicine, Gunma, JapanSearch for more papers by this authorToshio Fukuda, Toshio Fukuda Second Department of Pathology, Gunma University School of Medicine, Gunma, JapanSearch for more papers by this authorShogo Shinonome, Shogo Shinonome Third Department of Internal Medicine, Gunma University School of Medicine, Gunma, JapanSearch for more papers by this authorOsamu Ishikawa, Osamu Ishikawa Department of Dermatology, Gunma University School of Medicine, Gunma, JapanSearch for more papers by this authorTakuo Shirakura, Takuo Shirakura Department of Medicine, Kusatsu Branch Hospital, Gunma University School of Medicine, Gunma, JapanSearch for more papers by this author First published: July 1996 https://doi.org/10.1002/(SICI)1096-8652(199607)52:3 3.0.CO;2-ICitations: 10AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Abstract A 74-year-old Japanese man presented with systemic lymphadenopathy, hepatosplenomegaly, and erythroderma in December 1991. A characteristic pattern of anti-EBV antibodies was suggestive of latent EBV infection. A skin tumor biopsied in April 1993 contained biclonal EBV genomes diffusely in the infiltrate of polyclonal T cells and monoclonal B cells. The clinical course was rather mild in contrast to that of classical EBV-associated disorders. Our case was considered a rare indolent type of EBV-associated T-cell-rich B-cell lymphoma of the skin. © 1996 Wiley-Liss, Inc. References 1 Jones JF, Shurin S, Abramowsky C, Tubbs RR, Sciotto CG, Wahl R, Sands J, Gottman D, Katz BZ, Sklar J: T-cell lymphomas containing Epstein-Barr viral DNA in patients with chronic Epstein-Barr virus infections. N Engl J Med 318: 733, 1988. 2 Niedobitek G, Young LS: Epstein-Barr virus persistence and virus-associated tumours. Lancet 343: 333, 1994. 3 Su IJ, Hsieh HC, Lin KH, Uen WC, Kao CL, Chen CJ, Cheng AL, Kadin ME, Chen JY: Aggressive peripheral T-cell lymphomas containing Epstein-Barr viral DNA: A clinicopathologic and molecular analysis. Blood 77: 799, 1991. 4 Harabuchi Y, Yamanaka N, Kataura A, Imai S, Kinoshita T, Mizuno F, Osato T: Epstein-Barr virus in nasal T-cell lymphomas in patients with lethal midline granuloma. Lancet 335: 128, 1990. 5 Su IJ, Tsai TF, Cheng AL, Chen CC: Cutaneous manifestations of Epstein-Barr virus-associated T-cell lymphoma. J Am Acad Dermatol 29: 585, 1993. 6 Mueller N, Evans A, Harris NL, Comstock GW, Jerrum E, Magnus K, Orenreich N, Polk BF, Vogelman J: Hodgkin's disease and Epstein-Barr virus: Altered antibody pattern before diagnosis. N Engl J Med 320: 689, 1989. 7 Wn T-C, Mann RB, Epstein JI, MacMahon E, Lee WA, Charache P, Hayward SD, Kurman RJ, Hayward GS, Ambinder RF: Abundant expression of EBER1 small nuclear RNA in nasopharyngeal carcinoma. A morphologically distinctive target for detection of Epstein-Barr virus in formalin-fixed paraffin-embedded carcinoma specimens. Am J Pathol 138: 1461, 1991. 8 Baddoura FK, Chan WC, Masih AS, Mitchell D, Sun NCJ, Weisenburger DD: T-cell-rich B-cell lymphoma: A clinicopathologic study of eight cases. Am J Clin Pathol 103: 65, 1995. 9 Rodriguez J, Pugh WC, Cabanillas F: T-cell-rich B-cell lymphoma. Blood 82: 1586, 1993. 10 Loke SL, Ho F, Srivastava G, Fu KH, Leung B, Liang R: Clonal Epstein-Barr virus genome in T-cell-rich lymphomas of B or probable B lineage. Am J Pathol 140: 981, 1992. Citing Literature Volume52, Issue3July 1996Pages 221-223 ReferencesRelatedInformation

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