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Development of an optical imaging platform for functional imaging of small animals using wide-field excitation

2010; Optica Publishing Group; Volume: 1; Issue: 1 Linguagem: Inglês

10.1364/boe.1.000143

2156-7085

Vivek Venugopal, Jin Chen, Xavier Intes,

bioluminescence and chemiluminescence research

The design and characterization of a time-resolved functional imager using a wide-field excitation scheme for small animal imaging is described. The optimal operation parameters are established based on phantom studies. The performance of the platform for functional imaging and the simultaneous 3D reconstruction of absorption and scattering coefficients is investigated in vitro.