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The Synthetic Biology Open Language (SBOL) provides a community standard for communicating designs in synthetic biology

2014; Nature Portfolio; Volume: 32; Issue: 6 Linguagem: Inglês

10.1038/nbt.2891

1546-1696

Michal Galdzicki, Kevin Clancy, Ernst Oberortner, Matthew Pocock, Jacqueline Y. Quinn, César Rodríguez, Nicholas Roehner, Mandy Wilson, Laura Adam, J. Christopher Anderson, Bryan Bartley, Jacob Beal, Deepak Chandran, Joanna Chen, Douglas Densmore, Drew Endy, Raik Grünberg, Jennifer Hallinan, Nathan J. Hillson, Jeffrey D. Johnson, Allan Kuchinsky, Matthew W. Lux, Göksel Mısırlı, Jean Peccoud, Hector Plahar, Sirin Evren, Guy‐Bart Stan, Alan Villalobos, Anil Wipat, John H. Gennari, Chris J. Myers, Herbert M. Sauro,

Microbial Metabolic Engineering and Bioproduction

The re-use of previously validated designs is critical to the evolution of synthetic biology from a research discipline to an engineering practice. Here we describe the Synthetic Biology Open Language (SBOL), a proposed data standard for exchanging designs within the synthetic biology community. SBOL represents synthetic biology designs in a community-driven, formalized format for exchange between software tools, research groups and commercial service providers. The SBOL Developers Group has implemented SBOL as an XML/RDF serialization and provides software libraries and specification documentation to help developers implement SBOL in their own software. We describe early successes, including a demonstration of the utility of SBOL for information exchange between several different software tools and repositories from both academic and industrial partners. As a community-driven standard, SBOL will be updated as synthetic biology evolves to provide specific capabilities for different aspects of the synthetic biology workflow.