Artigo Acesso aberto Revisado por pares

Synthesis of the Erythrina Alkaloid 3-Demethoxyerythratidinone. Novel Acid-Induced Rearrangements of Its Precursors

2006; American Chemical Society; Volume: 8; Issue: 4 Linguagem: Inglês

10.1021/ol0527330

ISSN

1523-7060

Autores

Qiu Wang, Albert Padwa,

Tópico(s)

Organic and Inorganic Chemical Reactions

Resumo

[reaction: see text] A new strategy for the synthesis of 3-demethoxyerythratidinone has been developed and is based on an extraordinarily facile intramolecular Diels-Alder reaction of a 2-imido-substituted furan. During the course of the synthesis, several novel acid-induced rearrangement reactions were encountered.

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