Portal de Periódicos da CAPES

Targeted Drug Delivery for Cancer

2005; SAGE Publishing; Volume: 4; Issue: 4 Linguagem: Inglês

10.1177/153303460500400401

1533-0346

K. K. Jain,

RNA Interference and Gene Delivery

Cancer drug delivery is no longer simply wrapping the drug in new formulations for different routes of delivery. Knowledge and experience from other technologies such as nanotechnology, advanced polymer chemistry, and electronic engineering, are being brought together in developing novel methods of drug delivery. Advances in our knowledge of molecular biology of cancer and pathways involved in malignant transformation of cells are revolutionizing the approach to cancer treatment with a focus is on targeted cancer therapy. The newer approaches to cancer treatment not only supplement the conventional chemotherapy and radiotherapy but also aim to prevent damage to the normal tissues and overcome drug resistance. Innovative methods of cancer treatment require new concepts of drug delivery in cancer.