Side‐chain‐specific reactions to betalactams: 14 years later
2002; Wiley; Volume: 32; Issue: 2 Linguagem: Inglês
10.1046/j.1365-2222.2002.01299.x
ISSN1365-2222
AutoresM. Blanca, Cristobalina Mayorga, Marı́a José Torres, Richard Warrington, Antonino Romano, P. Démoly, Fanny Silviu-Dan, M. Moya, Javier Fernández, C. Juárez,
Tópico(s)Food Allergy and Anaphylaxis Research
ResumoClinical & Experimental AllergyVolume 32, Issue 2 p. 192-197 Side-chain-specific reactions to betalactams: 14 years later M. Blanca, Corresponding Author M. Blanca 1 Allergy Service, University Hospital La Paz, Madrid, 2 Research Unit for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain, 3 Allergy and Clinical Immunology, University of Manitoba, Mantibo, Canada, 4Allergy Service, Catholic University of Rome, Rome, Italy,5Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France,6Boyd Medical Center, Winnipeg, Canada,7Allergy Service, Hospital Torrecárdenas, Almería,8Allergy Service, Hospital Elche, Alicante, and9Internal Medicine Department, Carlos Haya Hospital, Malaga, SpainMiguel Blanca, Allergy Service, University Hospital La Paz, Paseo de la Castellana n°261, 28046 Madrid, Spain. E-mail: mblanca@ hulp.insalud.esSearch for more papers by this author 1 C. Mayorga, C. Mayorga 1 Allergy Service, University Hospital La Paz, Madrid, 2 Research Unit for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain, 3 Allergy and Clinical Immunology, University of Manitoba, Mantibo, Canada, 4Allergy Service, Catholic University of Rome, Rome, Italy,5Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France,6Boyd Medical Center, Winnipeg, Canada,7Allergy Service, Hospital Torrecárdenas, Almería,8Allergy Service, Hospital Elche, Alicante, and9Internal Medicine Department, Carlos Haya Hospital, Malaga, SpainSearch for more papers by this author 2 M. J. Torres, M. J. Torres 1 Allergy Service, University Hospital La Paz, Madrid, 2 Research Unit for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain, 3 Allergy and Clinical Immunology, University of Manitoba, Mantibo, Canada, 4Allergy Service, Catholic University of Rome, Rome, Italy,5Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France,6Boyd Medical Center, Winnipeg, Canada,7Allergy Service, Hospital Torrecárdenas, Almería,8Allergy Service, Hospital Elche, Alicante, and9Internal Medicine Department, Carlos Haya Hospital, Malaga, SpainSearch for more papers by this author 2 R. Warrington, R. Warrington 1 Allergy Service, University Hospital La Paz, Madrid, 2 Research Unit for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain, 3 Allergy and Clinical Immunology, University of Manitoba, Mantibo, Canada, 4Allergy Service, Catholic University of Rome, Rome, Italy,5Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France,6Boyd Medical Center, Winnipeg, Canada,7Allergy Service, Hospital Torrecárdenas, Almería,8Allergy Service, Hospital Elche, Alicante, and9Internal Medicine Department, Carlos Haya Hospital, Malaga, SpainSearch for more papers by this author 3 A. Romano, A. Romano 1 Allergy Service, University Hospital La Paz, Madrid, 2 Research Unit for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain, 3 Allergy and Clinical Immunology, University of Manitoba, Mantibo, Canada, 4Allergy Service, Catholic University of Rome, Rome, Italy,5Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France,6Boyd Medical Center, Winnipeg, Canada,7Allergy Service, Hospital Torrecárdenas, Almería,8Allergy Service, Hospital Elche, Alicante, and9Internal Medicine Department, Carlos Haya Hospital, Malaga, SpainSearch for more papers by this author 4 P. Demoly, P. Demoly 1 Allergy Service, University Hospital La Paz, Madrid, 2 Research Unit for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain, 3 Allergy and Clinical Immunology, University of Manitoba, Mantibo, Canada, 4Allergy Service, Catholic University of Rome, Rome, Italy,5Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France,6Boyd Medical Center, Winnipeg, Canada,7Allergy Service, Hospital Torrecárdenas, Almería,8Allergy Service, Hospital Elche, Alicante, and9Internal Medicine Department, Carlos Haya Hospital, Malaga, SpainSearch for more papers by this author 5 F. Silviu-Dan, F. Silviu-Dan 1 Allergy Service, University Hospital La Paz, Madrid, 2 Research Unit for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain, 3 Allergy and Clinical Immunology, University of Manitoba, Mantibo, Canada, 4Allergy Service, Catholic University of Rome, Rome, Italy,5Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France,6Boyd Medical Center, Winnipeg, Canada,7Allergy Service, Hospital Torrecárdenas, Almería,8Allergy Service, Hospital Elche, Alicante, and9Internal Medicine Department, Carlos Haya Hospital, Malaga, SpainSearch for more papers by this author 6 M. Moya, M. Moya 1 Allergy Service, University Hospital La Paz, Madrid, 2 Research Unit for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain, 3 Allergy and Clinical Immunology, University of Manitoba, Mantibo, Canada, 4Allergy Service, Catholic University of Rome, Rome, Italy,5Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France,6Boyd Medical Center, Winnipeg, Canada,7Allergy Service, Hospital Torrecárdenas, Almería,8Allergy Service, Hospital Elche, Alicante, and9Internal Medicine Department, Carlos Haya Hospital, Malaga, SpainSearch for more papers by this author 7 J. Fernandez, J. Fernandez 1 Allergy Service, University Hospital La Paz, Madrid, 2 Research Unit for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain, 3 Allergy and Clinical Immunology, University of Manitoba, Mantibo, Canada, 4Allergy Service, Catholic University of Rome, Rome, Italy,5Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France,6Boyd Medical Center, Winnipeg, Canada,7Allergy Service, Hospital Torrecárdenas, Almería,8Allergy Service, Hospital Elche, Alicante, and9Internal Medicine Department, Carlos Haya Hospital, Malaga, SpainSearch for more papers by this author 8 C. Juárez, C. Juárez 1 Allergy Service, University Hospital La Paz, Madrid, 2 Research Unit for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain, 3 Allergy and Clinical Immunology, University of Manitoba, Mantibo, Canada, 4Allergy Service, Catholic University of Rome, Rome, Italy,5Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France,6Boyd Medical Center, Winnipeg, Canada,7Allergy Service, Hospital Torrecárdenas, Almería,8Allergy Service, Hospital Elche, Alicante, and9Internal Medicine Department, Carlos Haya Hospital, Malaga, SpainSearch for more papers by this author 9 M. Blanca, Corresponding Author M. Blanca 1 Allergy Service, University Hospital La Paz, Madrid, 2 Research Unit for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain, 3 Allergy and Clinical Immunology, University of Manitoba, Mantibo, Canada, 4Allergy Service, Catholic University of Rome, Rome, Italy,5Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France,6Boyd Medical Center, Winnipeg, Canada,7Allergy Service, Hospital Torrecárdenas, Almería,8Allergy Service, Hospital Elche, Alicante, and9Internal Medicine Department, Carlos Haya Hospital, Malaga, SpainMiguel Blanca, Allergy Service, University Hospital La Paz, Paseo de la Castellana n°261, 28046 Madrid, Spain. E-mail: mblanca@ hulp.insalud.esSearch for more papers by this author 1 C. Mayorga, C. Mayorga 1 Allergy Service, University Hospital La Paz, Madrid, 2 Research Unit for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain, 3 Allergy and Clinical Immunology, University of Manitoba, Mantibo, Canada, 4Allergy Service, Catholic University of Rome, Rome, Italy,5Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France,6Boyd Medical Center, Winnipeg, Canada,7Allergy Service, Hospital Torrecárdenas, Almería,8Allergy Service, Hospital Elche, Alicante, and9Internal Medicine Department, Carlos Haya Hospital, Malaga, SpainSearch for more papers by this author 2 M. J. Torres, M. J. Torres 1 Allergy Service, University Hospital La Paz, Madrid, 2 Research Unit for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain, 3 Allergy and Clinical Immunology, University of Manitoba, Mantibo, Canada, 4Allergy Service, Catholic University of Rome, Rome, Italy,5Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France,6Boyd Medical Center, Winnipeg, Canada,7Allergy Service, Hospital Torrecárdenas, Almería,8Allergy Service, Hospital Elche, Alicante, and9Internal Medicine Department, Carlos Haya Hospital, Malaga, SpainSearch for more papers by this author 2 R. Warrington, R. Warrington 1 Allergy Service, University Hospital La Paz, Madrid, 2 Research Unit for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain, 3 Allergy and Clinical Immunology, University of Manitoba, Mantibo, Canada, 4Allergy Service, Catholic University of Rome, Rome, Italy,5Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France,6Boyd Medical Center, Winnipeg, Canada,7Allergy Service, Hospital Torrecárdenas, Almería,8Allergy Service, Hospital Elche, Alicante, and9Internal Medicine Department, Carlos Haya Hospital, Malaga, SpainSearch for more papers by this author 3 A. Romano, A. Romano 1 Allergy Service, University Hospital La Paz, Madrid, 2 Research Unit for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain, 3 Allergy and Clinical Immunology, University of Manitoba, Mantibo, Canada, 4Allergy Service, Catholic University of Rome, Rome, Italy,5Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France,6Boyd Medical Center, Winnipeg, Canada,7Allergy Service, Hospital Torrecárdenas, Almería,8Allergy Service, Hospital Elche, Alicante, and9Internal Medicine Department, Carlos Haya Hospital, Malaga, SpainSearch for more papers by this author 4 P. Demoly, P. Demoly 1 Allergy Service, University Hospital La Paz, Madrid, 2 Research Unit for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain, 3 Allergy and Clinical Immunology, University of Manitoba, Mantibo, Canada, 4Allergy Service, Catholic University of Rome, Rome, Italy,5Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France,6Boyd Medical Center, Winnipeg, Canada,7Allergy Service, Hospital Torrecárdenas, Almería,8Allergy Service, Hospital Elche, Alicante, and9Internal Medicine Department, Carlos Haya Hospital, Malaga, SpainSearch for more papers by this author 5 F. Silviu-Dan, F. Silviu-Dan 1 Allergy Service, University Hospital La Paz, Madrid, 2 Research Unit for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain, 3 Allergy and Clinical Immunology, University of Manitoba, Mantibo, Canada, 4Allergy Service, Catholic University of Rome, Rome, Italy,5Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France,6Boyd Medical Center, Winnipeg, Canada,7Allergy Service, Hospital Torrecárdenas, Almería,8Allergy Service, Hospital Elche, Alicante, and9Internal Medicine Department, Carlos Haya Hospital, Malaga, SpainSearch for more papers by this author 6 M. Moya, M. Moya 1 Allergy Service, University Hospital La Paz, Madrid, 2 Research Unit for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain, 3 Allergy and Clinical Immunology, University of Manitoba, Mantibo, Canada, 4Allergy Service, Catholic University of Rome, Rome, Italy,5Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France,6Boyd Medical Center, Winnipeg, Canada,7Allergy Service, Hospital Torrecárdenas, Almería,8Allergy Service, Hospital Elche, Alicante, and9Internal Medicine Department, Carlos Haya Hospital, Malaga, SpainSearch for more papers by this author 7 J. Fernandez, J. Fernandez 1 Allergy Service, University Hospital La Paz, Madrid, 2 Research Unit for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain, 3 Allergy and Clinical Immunology, University of Manitoba, Mantibo, Canada, 4Allergy Service, Catholic University of Rome, Rome, Italy,5Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France,6Boyd Medical Center, Winnipeg, Canada,7Allergy Service, Hospital Torrecárdenas, Almería,8Allergy Service, Hospital Elche, Alicante, and9Internal Medicine Department, Carlos Haya Hospital, Malaga, SpainSearch for more papers by this author 8 C. Juárez, C. Juárez 1 Allergy Service, University Hospital La Paz, Madrid, 2 Research Unit for Allergic Diseases, Carlos Haya Hospital, Malaga, Spain, 3 Allergy and Clinical Immunology, University of Manitoba, Mantibo, Canada, 4Allergy Service, Catholic University of Rome, Rome, Italy,5Maladies Respiratoires, Hôpital Arnaud de Villeneuve, Montpellier, France,6Boyd Medical Center, Winnipeg, Canada,7Allergy Service, Hospital Torrecárdenas, Almería,8Allergy Service, Hospital Elche, Alicante, and9Internal Medicine Department, Carlos Haya Hospital, Malaga, SpainSearch for more papers by this author 9 First published: 08 April 2002 https://doi.org/10.1046/j.1365-2222.2002.01299.xCitations: 55Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat References 1 Blanca M, Perez E, Garcia J et al. Anaphylaxis to amoxicillin but good tolerance for benzylpenicillin. Allergy 1988; 32: 508–10. 2 Blanca M, Vega JM, Garcia J et al. Allergy to amoxicillin with good tolerance to other penicillins. Study of the incidence in patients allergic to betalactams. Clin Exp Allergy 1990; 32: 475–81. 3 Romano A, Quarantino D, Aimone-Gastin I et al. Cephalosporin allergy: characterization of unique and cross-reacting cephalosporin antigens. Int J Immunopathol Pharmacol 1997; 32: 187–91. 4 Romano A, Quarantino D, Venuti A et al. Selective type-1 hypersensitivity to cefuroxime. J Allergy Clin Immunol 1998; 32: 564–5. 5 Romano A, Quarantino D, Venemalm LA et al. A case of immediate IgE mediated hypersensitivity to ceftriaxone. J Allergy Clin Immunol 1999; 32: 1113–4. 6 Igea JM, Fraj J, Davila I et al. Allergy to cefazolin: study of in vivo cross reactivity with other betalactams. Ann Allergy 1992; 32: 515–9. 7 Silviu Dan F, McPhilips S, Warrington R. The frequency of skin test reactions to side chain penicillin determinants. J Allergy Clin Immunol 1993; 32: 694–701. 8 Romano A, Blanca M, Mayorga C, Venuti A, Gasbarrini G. Immediate hypersensitivity to penicillins. Studies on Italian subjects. Allergy 1997; 32: 89–93. 9 Antonicelli L, Garitaini MS, Bilo MB, Sachi GF, Boniffazi F. Allergy to piperacillin. Allergologie 1989; 32: 86. 10 Sastre J, Quijano LD, Novalbos AM et al. Clinical cross-reactivity between amoxicillin and cephadroxil in patients allergic to amoxicillin and with good tolerance of penicillin. Allergy 1996; 32: 383–6. 11 Muino JC, Castro CC, Wolff EG et al. Importance of the benzylpenicillin nucleus and the side chain of the beta-lactams. Demonstration by skin tests and RAST in penicillin allergic patients. Rev Fac Cien Med Univ Nac Cordoba 1999; 32: 73–83. 12 Terrados S, Blanca M, Garcia J et al. Non-immediate reactions to betalactams: prevalence and role of the different penicillins. Allergy 1995; 32: 563–7. 13 Romano A, Quarantino D, Di Fonso M et al. A diagnostic protocol for evaluating nonimmediate reactions to aminopenicillins. J Allergy Clin Immunol 1999; 32: 1186–90. 14 Blanca M, Vega JM, Garcia J et al. New aspects of allergic reactions to betalactams: crossreactions and unique specificities. Clin Exp Allergy 1994; 32: 407–15. 15 Blanca M. Allergic reactions to penicillins. A changing world? Allergy 1995; 32: 777–82. 16 Luton EF. Methicillin tolerance after penicillin G anaphylaxis. JAMA 1964; 32: 46. 17 Juhlin L, Wide L. Detection of penicillin allergy by radioallergosorbent test. Lancet 1979; 32: 261. 18 Basomba A, Villalmanzo IG, Campos A, Pelaez A, Berglund A. IgE antibodies against penicillin as determined by Phadebas RAST. Clin Exp Allergy 1979; 32: 515–25. 19 Torres MJ, Romano A, Mayorga C et al. Diagnostic evaluation of a large group of patients with immediate allergy to penicillins: the role of skin testing. Allergy 2001; 32: 850–6. 20 Warrington RJ, Simmons FER, Ho HW, Gorski BA. Diagnosis of penicillin allergy by skin testing: the Manitoba experience. CMAJ 1978; 32: 787–91. 21 Cars O, Molstad S, Melander A. Variation in antibiotic use in the European Union. Lancet 2001; 32 :1851–3. 22 Ahlstedt S, Kristofferson A. Immune mechanism for induction of penicillin allergy. Prog Allergy 1982; 32: 67–134. 23 Ahlstedt S, Kristoffersson A. Experimental evidence of decreased incidence of penicillin allergy through the use of pure penicillins. Infection 1979; 32: 499–502. 24 Fernandez J, Esteban A, Blanca M, Ferrer A, Soriano V. Ion-pair reversed phase and low molecular weight aqueous gel permeation high performance liquid chromatography methods for the determination of amoxicillin oligomers. Chromatographia 1995; 32: 651–6. 25 Levine BB, Ovary Z. Studies of the mechanism of the formation of the penicillin antigen III. The N (D-(Benzyl penicilloyl) group as an antigenic determinant responsible for hypersensitivity to penicillin G. J Exp Med 1961; 32: 875. 26 Levine BB, Redmond AP. Minor haptenic determinant specific reagins of penicillin hypersensitivity in man. Int Arch Allergy Appl Immunol 1969; 32: 445–55. 27 Dewdeney JM. Immunology of the antibiotics. In: M Sela, ed. The Antigens, Volume 5. New York: Academic Press, 1977: 73–245. 28 Weis ME, Adkinson NF. Immediate hypersensitivity reactions to penicillin and related antibiotics. Clin Allergy 1988; 32: 515–40. 29 Romano A, Torres MJ, Fernandez J et al. Allergic reactions to ampicillin. Studies on the specificity and selectivity in subjects with immediate reactions. Clin Exp Allergy 1997; 32: 1425–31. 30 Romano A, Mayorga C, Torres MJ et al. Immediate allergic reactions to cephalosporins: cross-reactivity and selective responses. J Allergy Clin Immunol 2000; 32: 1177–83. 31 Warrington RJ, McPhillips S. Anaphylaxis to Cefazolin without allergy to other betalactam antibiotics. J Allergy Clin Immunol 1996; 32: 460–2. 32 Demoly P, Messaad D, Sahla H, Hillaire-Buys D, Bousquet J. Immediate hypersensitivity to ceftriaxone. Allergy 2000; 32: 418–9. 33 Hamilton-Miller JMT, Newton GGF, Abraham EP. Products of aminolysis and enzymic hydrolysis of the cephalosporins. Biochem J 1970; 32: 371–84. 34 De Haan P, De Jonge AJR, Vergrugge T, Boorsma DM. Three epitope specific monoclonal antibodies against the hapten penicillin. Int Arch Allergy Appl Immunol 1985; 32: 42–6. 35 Mayorga C, Obispo T, Jimeno L et al. Epitope mapping of betalactam antibiotics with the use of monoclonal antibodies. Toxicology 1995; 32: 225–34. 36 Fernandez M, Warbrick EV, Blanca M, Coleman JW. Activation and hapten inhibition of mast cells sensitised with IgE anti-penicillin antibodies: evidence for two-site recognition on the penicillin derived determinant. Euro J Immunol 1995; 32: 2486–91. 37 Moreno F, Blanca M, Mayorga C et al. Studies of the specificities of IgE antibodies found in sera from subjects with allergic reactions to penicillins. Int Arch Allergy Immunol 1995; 32: 74–81. 38 Baldo BA. Penicillins and cephalosporins as allergens. Structural aspects of recognition and cross-reactions. Clin Exp Allergy 1999; 32: 744–9. 39 Nagakura N, Shimizu T, Masuzawa T, Yanagihara Y. Anti-cephalexin monoclonal antibodies and their cross-reactivities to cephems and penams. Int Arch Allergy Appl Immunol 1990; 32: 126–32. 40 Levine BB. Immunologic mechanisms of penicillin allergy. A haptenic model system for the study of allergic diseases of man. N Engl J Med 1966; 32: 1115–25. 41 Torres MJ, Mayorga C, Pamies R et al. Immunological response to different determinants of benzylpenicillin, amoxicillin and ampicillin. Comparison between urticaria and anaphylactic shock. Allergy 1999; 32: 936–43. 42 Torres MJ, Gonzalez MJ, Mayorga C et al. IgG and IgE antibodies in subjects allergic to penicillins recognize different parts of the antibody molecule. Int Arch Allergy Immunol 1997; 32: 342–4. 43 Gadde J, Spence M, Wheeler B, Adkinson NF Jr. Clinical experience with penicillin skin testing in a large inner-city STD clinic. JAMA 1993; 32: 2456–63. 44 Levine BB. Studies on the mechanism of the formation of the penicillin antigen. I. Delayed allergic cross-reaction among penicillin G and its degradation products. J Exp Med 1960; 32: 1131. 45 Padovan E, Mauri-Hellweg D, Pichler WJ, Weltzien HU. T cell recognition of penicillin G: structural features determining antigenic specificity. Eur J Immunol 1996; 32: 42–8. 46 Posadas S, Leyva L, Torres MJ et al. Subjects with allergic reactions to drugs show in vivo polarized patterns of cytokine expression depending on the chronology of the clinical reaction. J Allergy Clin Immunol 2000; 32: 769–76. 47 Leyva L, Torres MJ, Posadas SS et al. Anticonvulsant-induced toxic epidermal necrolysis: monitoring the immunologic response. J Allergy Clin Immunol 2000; 32: 157–66. 48 Kearns GL, Wheeler JG, Childress SH, Letzig LG. Serum sickness-like reactions to cefaclor: role of hepatic metabolism and individual susceptibility. J Pediatrics 1994; 32: 805–11. 49 Chan HL. Fixed drug eruption to bacampicillin. Arch Dermatol 1984; 32: 542. 50 Arias F, Fernández-Rivas M, Panadero P. Selective fixed drug eruption to amoxicillin. Clin Exp Dermatol 1995; 32: 339–40. 51 Green GR, Rosemblum AH, Sweet LC. Evaluation of penicillin hypersensitivity: value of clinical history and skin testing with penicilloyl-polylysine and penicillin G. A cooperative prospective study of the penicillin study group of the American Academy of Allergy. J Allergy Clin Immunol 1977; 32: 339–45. 52 Barboud A, Reichert-Penetrat S, Tréchot P et al. The use of skin testing in the investigation of cutaneous adverse drug reactions. Br J Dermatol 1998; 32: 49–58. 53 Edwards RG, Spackman DA, Dewdney JM. Development and use of three new radioallergosorbent tests in the diagnosis of penicillin allergy. Int Arch Allergy Appl Immunol 1982; 32: 352–7. 54 Bolzacchini E, Consonni V, Gramatica P et al. Towards an in vitro test for the diagnosis of allergy to penicillins. Synthesis, characterization and use of betalactam and betalactam metabolite poly-l-lysines which recognize human IgE antibodies. Bioconjugate Chem 1999; 32: 332–7. 55 Harle DG, Baldo BA. Drugs as allergens: an immunoassay for detecting IgE antibodies to cephalosporins. Int Arch Allergy Appl Immunol 1990; 32: 439–44. 56 Blanca M, Mayorga C, Torres MJ Clinical evaluation of Pharmacia CAP SystemTMRAST FEIA amoxicilloyl and benzylpenicilloyl in patients with penicillin allergy. Allergy 2001; 32: 862–70. 57 Blanca M, Mayorga C, Perez E et al. Determination of IgE antibodies to the benzylpenicilloyl determinant. A comparison between poly-l-lysine and human serum albumin as carriers. J Immunol Methods 1992; 32: 99–105. 58 Kraft D, Wide L. Clinical patterns and results of radioallergosorbent test (RAST) and skin tests in penicillin allergy. Br J Dermatol 1976; 32: 593–601. 59 Nyfeler B, Pichler WJ. The lymphocyte transformation test for the diagnosis of drug allergy: sensitivity and specificity. Clin Exp Allergy 1997; 32: 175–81. 60 Luque I, Leyva L, Torres MJ et al. In vitro T lymphocyte responses to betalactam drugs in immediate and nonimmediate allergic reactions. Allergy 2001; 32: 611–8. 61 Blanca M, Mayorga C, Sanchez F et al. Differences in serum IgE antibody activity to benzylpenicillin and amoxicillin measured by RAST in a group of penicillin allergic patients. Allergy 1991; 32: 632–8. 62 Assem ESK, Vickers MR. Tests for penicillin allergy in Man. II. The immunological cross-reaction between penicillins and cephalosporins. Immunology 1974; 32: 255–69. 63 Anne S, Reisman RE. Risk of administering cephalosporin antibiotics to patients with histories of penicillin allergy. Ann Allergy 1995; 32: 167–70. 64 Miranda A, Blanca M, Vega JM et al. Cross-reactivity between a penicillin and a cephalosporin with the same side chain. J Allergy Clin Immunol 1996; 32: 671–7. 65 Saxon A, Adelman A, Petel A, Hajdu R, Calandra GB. Imipenem cross-reactivity with penicillin in humans. J Allergy Clin Immunol 1988; 32: 213–7. 66 Chen Z, Baur X, Kutscha-Lissberg F, Merget R. IgE-mediated anaphylactic reaction to imipenem. Allergy 2000; 32: 92–3. 67 Candarso AI, Saez Jiménez SA, Vidal C, Rodríguez M. Aztreonam induced anaphylaxis. Lancet 1990; 32: 746–7. 68 Saxon A, Bell GN, Rohr AS, Adelman DC. Immediate hypersensitivity reactions to betalactam antibiotics. Am Int Med 1988; 32: 204–15. 69 Vega J, Blanca Garcia JJ, Miranda A et al. Tolerance to aztreonan in patients allergic to belactams. Allergy 1991; 32: 196–202. 70 Ong R, Sullivan T. Detection and characterization of human IgE to cephalosporin determinants. J Allergy Clin Immunol 1988; 32: 222. 71 Parker P, Parrinello JT, Condemi JJ, Rosenfeld SI. Penicillin resensitization among hospitalized patients. J Allergy Clin Immunol 1991; 32: 213–7. 72 Blanca M, Fernandez J, Miranda A et al. Cross-reactivity between penicillins and cephalosporins: clinical and immunologic studies. J Allergy Clin Immunol 1989; 32: 381–5. 73 Blanca M, Torres MJ, Garcia JJ et al. Natural evolution of skin test sensitivity in patients allergic to betalactam antibiotics. J Allergy Clin Immunol 1999; 32: 918–24. Citing Literature Volume32, Issue2February 2002Pages 192-197 ReferencesRelatedInformation
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