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Asystole complicating physostigmine treatment of tricyclic antidepressant overdose

1980; Elsevier BV; Volume: 9; Issue: 11 Linguagem: Inglês

10.1016/s0196-0644(80)80232-0

1097-6760

Paul R. Pentel, Charles D. Peterson,

Alcoholism and Thiamine Deficiency

Physostigmine is a commonly used therapy for the anticholinergic manifestations of tricyclic antidepressant (TCA) overdose. We describe two patients with TCA toxicity who developed asystole following the administration of physostigmine to treat seizures. Physostigmine is a commonly used therapy for the anticholinergic manifestations of tricyclic antidepressant (TCA) overdose. We describe two patients with TCA toxicity who developed asystole following the administration of physostigmine to treat seizures.