Effect of taurine administration on liver lipids in guinea pig
1986; Birkhäuser; Volume: 42; Issue: 4 Linguagem: Inglês
10.1007/bf02118631
ISSN0014-4754
AutoresAlfredo Cantàfora, Alberto Mantovani, Roberta Masella, Luca Mechelli, Domenico Alvaro,
Tópico(s)Muscle metabolism and nutrition
ResumoThe oral administration of 0.4% taurine in drinking water for 14 consecutive days showed the following hepatic effects in male guinea pig. The percentage of tauro-conjugated biliary bile acids was increased from 17.2-54.2%; the ratio liver weight/body weight was increased, and fatty change was induced. Liver triglyceride concentration was accordingly increased; diglyceride and phosphatidylcholine concentrations were reduced by the treatment, while phosphatidylethanolamine level was not affected. These changes suggest an adverse effect of taurine administration on phosphatidylcholine hepatic synthesis.
Referência(s)