PLASMINOGEN ACTIVATOR‐DEPENDENT PERICELLULAR PROTEOLYSIS
1991; Wiley; Volume: 79; Issue: 4 Linguagem: Espanhol
10.1111/j.1365-2141.1991.tb08078.x
ISSN1365-2141
Autores Tópico(s)Protease and Inhibitor Mechanisms
ResumoBritish Journal of HaematologyVolume 79, Issue 4 p. 537-543 PLASMINOGEN ACTIVATOR-DEPENDENT PERICELLULAR PROTEOLYSIS Michael F. Scully, Corresponding Author Michael F. Scully Thrombosis Research Institute, LondonDr Michael F. Scully, Thrombosis Research Institute, Emmanuel Kaye Building, Manresa Road, Chelsea, London SW3 6LR.Search for more papers by this author Michael F. Scully, Corresponding Author Michael F. Scully Thrombosis Research Institute, LondonDr Michael F. Scully, Thrombosis Research Institute, Emmanuel Kaye Building, Manresa Road, Chelsea, London SW3 6LR.Search for more papers by this author First published: December 1991 https://doi.org/10.1111/j.1365-2141.1991.tb08078.xCitations: 15AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES Andreasen, P. A., Georg, B., Lund, L. R., Riccio, A. & Stacey, S. N. (1990) Plasminogen activator inhibitors: hormonally-regulated serpins. Molecular and Cellular Endocrinology, 68, 1–19. Behrendt, N., Ploug, M., Patthy, L., Houen, G., Blasi, F. & Dano, K. (1991) The ligand binding domain of the cell surface receptor for urokinase-type plasminogen activator. Journal of Biological Chemistry, 266, 7842–7847. Behrendt, N., Ronne, E., Ploug, M., Petri, T., Lober, D., Nielsen, L. S., Schleuning, W. D., Blasi, F., Appella, E. & Dano, K. (1990) The human receptor for urokinase plasminogen activator. NH2-terminal amino acid sequence and glycosylation variants. Journal of Biological Chemistry, 265, 6453–6460. Bell, S. M., Brackenberg, R. W., Leslie, N. D. & Degen, J. L. (1990) Plasminogen activator gene expression is induced by the src oncogene product and tumour promoters. Journal of Biological Chemistry, 265, 1333–1338. Blasi, F. (1988) Surface receptors for urokinase plasminogen activator. Fibrinolysis, 2, 73–84. Blasi, F., Vassalli, J-D. & Dano, K. (1987) Urokinase-type plasminogen activators. Proenzyme, receptors and inhibitors. Journal of Cell Biology, 104, 801–804. Boyd, D. (1989) Examination of the effects of epidermal growth factor on the production of urokinase and the expression of the plasminogen activator receptor in a human colon cancer cell line. Colon, 49, 2427–2432. Burnathan, E. S., Kuo, A., Kariko, K., Rosenfeld, L., Murray, S. C., Behrendt, N., Ronne, E., Weiner, D., Henkin, J. & Cines, D. B. (1990) Characterization of human endothelial cell urokinase-type plasminogen activator receptor protein and messenger RNA. Blood, 76, 1795–1806. Busio, N., Huarte, J., Vassalli, J-D., Sappino, A. P. & Belin, D. (1989) Plasminogen activation in the mouse mammary gland. Decreased expression during lactation. Journal of Biological Chemistry, 264, 7455–7457. Cajot, J. F., Bamat, J., Bergonzelli, G. E., Kruithof, E. K., Medcalf, R. L. Testuz, J. & Sordat, B. (1990) Plasminogen activator inhibitor type 1 is a potent natural inhibitor of extracellular matrix degradation by fibrosarcoma and colon carcinoma. Proceedings of the National Academy of Sciences of the United States of America, 87, 6939–6943. Cannio, R., Rennie, P. S. & Blasi, F. (1991) A cell-type specific and enhancer-dependent silencer in the regulation of the expression of the human urokinase plasminogen activator gene. Nucleic Acids Research, 19, 2303–2309. Chapman, H. A., Yang, X., Sailor, L. Z. & Sugarbaker, D. J. (1991) Developmental expression of plasminogen activator inhibitor type 1 by human alveolar macrophages. Possible role in lung injury. Journal of Immunology, 145, 3398–3405. Clowes, A. C., Clowes, M. M., Au, Y. P. T., Reidy, M. A. & Belin, D. (1990) Smooth muscle cells express urokinase during mitogenesis and tissue-type plasminogen activator during migration in injured rat carotid artery. Circulation, 67, 61–67. Dano, K., Andreasen, P. A., Grondahl-Hansen, J., Kristensen, P., Nielsen, L. S. & Skriver, L. (1985) Plasminogen activators, tissue degradation and cancer. Advances in Cancer Research, 44, 139–266. Duffy, M. J., Reilly, D., O'Sullivan, C., O'Higgins, N. & Fennelly, J. J. (1990) Urokinase-plasminogen activator and prognosis in breast cancer. Lancet, 335, 108. Ellis, V., Behrendt, N. & Dano, K. (1991) Plasminogen activation by receptor-bound urokinase. A kinetic study with both cell-associated and isolated receptor. Journal of Biological Chemistry, 266, 12752–12758. Ellis, V., Scully, M. F. & Kakkar, V. V. (1987) Plasminogen activation by single chain urokinase in functional isolation. A kinetic study. Journal of Biological Chemistry, 262, 14998–15003. Ellis, V., Scully, M. F. & Kakkar, V. V. (1989) Plasminogen activation initiated by single-chain urokinase-type plasminogen activator. Potentiation by U937 monocytes. Journal of Biological Chemistry, 264, 2185–2188. Estreicher, A., Mühlhauser, J., Carpentier, J. L., Orci, L. & Vassalli, J. D. (1990) The receptor for urokinase type plasminogen activator polarizes expression of the protease to the leading edge of migrating monocytes and promotes degradation of enzyme inhibitor complexes. Journal of Cell Biology, 111, 783–792. Grondahl-Hansen, J., Ralfkiaen, E., Kirkeby, L. T., Kristensen, P., Lund, L. R. & Dano, K. (1991) Localization of urokinase type plasminogen activator in stromal cells in adenocarcinomas of the colon in humans. American Journal of Pathology, 138, 111–117. Hajar, K. A. & Hamel, N. M. (1990) Identification and characterization of human endothelial cell membrane binding sites for tissue plasminogen activator and urokinase. Journal of Biological Chemistry, 265, 2908–2916. Hamilton, J. A., Vairo, G., Knight, K. R. & Cocks, B. J. (1991) Activation and proliferation signals in murine macrophages. Biochemical signals controlling the regulation of macrophage: urokinase type plasminogen activator activity by colony-stimulating factors and other agents. Blood, 77, 618–627. Hamaguchi, M., Morishita, Y., Takahashi, I., Ogura, M., Takamatsu, J. & Saito, H. (1991) FDP-D dimer induces the secretion of interleukin 1. urokinase-type plasminogen activator and plasminogen activator inhibitor-2 in a human promonocyte leukemic cell line. Blood, 77, 94–100. Hantai, D., Rao, J. S., Kahler, C. & Restoff, R. (1989) Decrease in plasminogen activator correlates with synapse elimination during neonatal development of mouse skeletal muscle. Proceedings of the National Academy of Science of the United States of America, 86, 362–366. Hart, P. H., Vitti, G. F., Burgess, D. R., Whitty, G. A., Royston, K. & Hamilton, J. A. (1991) Activation of human monocytes by granulocyte-macrophage colony stimulating factor: increased urokinase type plasminogen activator activity. Blood, 77, 841–848. He, C., Wilhelm, S. M., Pentland, A. P., Marmer, B. L., Grant, G. A., Eisen, A. Z. & Goldberg, G. I. (1989) Tissue cooperation in a proteolytic cascade activating human interstitial collagenase. Proceedings of the National Academy of Sciences of the United States of America, 86, 2632–2636. Van Hinsbergh, V. W. M., van der Berg. E. A., Friers. W. & Dooijewaard, G. (1990) Tumour necrosis factor induces the production of urokinase type plasminogen activator by human endothelial cells. Blood, 75, 1991–1998. Holmes, W. E., Pennica, D., Blaber, M., Rey, M. W., Guenzler, W. A., Steffens, G. J. & Heyneker, H. L. (1985) Cloning and expression of the gene for pro-urokinase in Escherichia coli. Biotechnology, 3, 923–929. Ingber, D. E. & Folkman, J. (1987) Mechanochemical switching between growth and differentiation during fibroblast growth factor stimulated angiogenesis in vitro: role of extracellular matrix. Journal of Cell Biology, 109, 317–330. Janicke, F., Schmitt, M., Ulm, K., Gossner, W. & Graeff, H. (1989) Urokinase-type plasminogen activator (u-PA) antigen and early relapse in breast cancer. Lancet, ii, 1049. Jankum, J., Maher, V. M. & McCormick, J. J. (1991) Malignant transformation of human fibroblasts correlates with increased activity of receptor bound plasminogen activator. Cancer Research, 51, 1221–1226. Kirchheimer, J. C., Binder, B. D. & Remold, H. G. (1990) Matrix-bound plasminogen activation inhibitor type 1 inhibits invasion of human monocytes into interstitial tissue. Journal of Immunology, 145, 1518–1522. Kristensen, P., Eriksen, J. & Dano, K. (1991) Localization of urokinase-type plasminogen activator messenger RNA in the normal mouse by in situ hybridization. Journal of Histochemistry and Cytochemistry, 39, 341–349. Laiko, M. & Keski-Oja, J. (1989) Growth factors in the regulation of pericellular proteolysis. A review. Cancer Research, 49, 2533–2553. Lijnen, H. R. & Collen, D. (1991) Towards the development of improved thrombolytic agents. (Annotation). British Journal of Haematology, 77, 261–266. Lijnen, H. R., Van Hoef, B., Nelles, L. & Collen, D. (1990) Plasminogen activation with single chain urokinase type plasminogen activator (scu-PA). Studies with active site mutagenized plasminogen (Ser 740 → Ala) and plasmin resistant scu-PA (Lys 158 → Glu). Journal of Biological Chemistry, 265, 5232–5236. Lund, L. F., Ronne, E., Roldan, A. L., Behrendt, N., Romer, J., Blasi, F. & Dano, K. (1991a) Urokinase receptor mRNA level and gene transcription are strongly and rapidly increased by phorbol myristate activity in human monocyte-like U937 cells. Journal of Biological Chemistry, 266, 5177–5181. Lund, L. R., Romer, J., Blom, K., Skenstrup, M., Ronne, E., Ellis, V., Blasi, F. & Dano, K. (1991b) The receptor for urokinase-type plasminogen activator: Regulation of gene expressions by hormones, growth factors and tumour promoters in human cell lines. 3rd International Workshop on Molecular and Cellular Biology of Plasminogen Activation, Elsinore, Denmark, May 1991. Abstract 136. Marshall, B. C., Sagese, D. S., Roo, N. V., Emmi, M. & Hoida, J. R. (1990) Alveolar epithelial cell plasminogen activator. Characterization and regulation. Journal of Biological Chemistry, 265, 8198–8204. Medcalf, R. L., Ruegg, M. & Schleuning, W. D. (1990) A DNA motif related to the cAMP-responsive element and an exon located activator protein-2 binding site in the human tissue-type plasminogen activator gene promoter cooperate in basal expression and convey activation by phorbol ester and cAMP. Journal of Biological Chemistry, 265, 14618–14626. Meissauer, A., Kramer, M. D., Hofmann, M., Erkell, L. J., Jacob, E., Schirrmacher, V. & Brunner, G. (1991) Urokinase-type and tissue-type plasminogen activators are essential for in vitro invasion of human melanoma cells. Experimental Cell Research, 192, 453–459. Mignatti, P., Mazzieri, R. & Rifkin, D. B. (1991) Expression of the urokinase receptor in vascular endothelial cells is stimulated by basic fibroblast growth factor. Journal of Cell Biology, 113, 1193–1201. Miles, L. A., Dahlberg, C. M., Plescia, J., Felez, J. & Kato, J. (1991) Role of cell surface lysines in plasminogen binding to cells: Identification of alpha-Enolase as a candidate plasminogen receptor. Biochemistry, 30, 1682–1691. Morton, P. A., Owensby, D. A., Wun, T. C., Billadello, J. J. & Schwartz, A. L. (1990) Identification of determinants involved in binding of tissue-type plasminogen activator-plasminogen activator inhibitor type 1 complexes to Hep G-2 cells. Journal of Biological Chemistry, 265, 14093–14099. Nagamine, Y. & Ziegler, A. (1991) Okadaic acid induction of the urokinase-type plasminogen activator gene occurs independently of cAMP-dependent protein kinase and protein kinase C and is sensitive to protein synthesis inhibitors. EMBO Journal, 10, 117–122. Nusrat, A. R., Chapman, H. A., Jr (1991) An autocrine role for urokinase in phorbol ester mediated differentiation of myeloid cell lines. Journal of Clinical Investigation, 87, 1091–1097. Ny, T., Ohlsson, M., Peng, X-R., Liu, Y-X., Jia, X-C. & Hsuel, A. J. W. (1991) The hormonally controlled regulation of t-PA and PAI-1 gene expression in the ovary mediates an extracellular proteolytic activity that leads to ovulation. (Abstract). Thrombosis and Haemostasis, 65, 807. Nykjaer, A., Jensen, P. H., Petersen, C. M., Moller, B., Christensen, E., Ebbesen, P., Gliemann, J. & Andreasen, P. A. (1991) Cell and ligand-specific receptor-binding and endocytosis of u-PA and u-PA/inhibitor complexes in human blood cells and trophoblastic cell lines. 3rd International Workshop on Molecular and Cellular Biology of Plasminogen Activation, Elsinore, Denmark, May 1991, Abstract 7. Ossowski, L. (1988a) Plasminogen activation-dependent pathway in the dissemination of human tumour cells in the chick embryo. Journal of Cell Biology, 107, 2437–2445. Ossowski, L. (1988b) Plasminogen activator-dependent pathway in the dissemination of human tumour cells in the chick embryo. Cell, 52, 321–328. Ossowski, L., Russo-Payne, H. & Wilson, E. L. (1991) Inhibition of urokinase type-plasminogen activation by antibodies. The effect on dissemination of a human tumour in the nude mouse. Cancer Research, 51, 274–281. Pennica, D., Holmes, W. E., Kohr, W. J., Harkins, R. N., Vehar, G. A., Ward, C. A., Bennett, W. F., Yelverton, E., Seeburg, P. H., Heyneker, H. L., Goeddel, D. V. & Collen, D. (1983) Cloning and expression of human tissue type plasminogen activator cDNA in E. Coli. Nature, 301, 214–221. Pepper, M. S., Belin, D., Montesano, R., Orci, L. & Vassalli, J-D. (1990) Transforming growth factor-beta 1 modulates basic fibroblast growth factor induced proteolytic and angiogenic properties of endothelial cells in vitro. Journal of Cell Biology, 108, 693–702. Plesner, T., Wittrup, M., Ploug, M., Ronne, E., Dano, K., Carlsen, K., Gram, J. & Johnsen, H. (1991) Expression of urokinase-type plasminogen activator receptor on blood and bone marrow cells. 3rd International Workshop on Molecular and Cellular Biology of Plasminogen Activation Elsinore, Denmark, May 1991, Abstract 177. Ploug, M., Ronne, E., Behrendt, N., Jensen, A. L., Blasi, F., Dano. K. (1991a) Cellular receptor for urokinase-type plasminogen activator. Carboxyl terminal processing and membrane anchoring by glycosylphosphatidyl inositol. Journal of Biological Chemistry, 266, 1926–1933. Ploug, M., Behrendt, N., Plesner, T., Ronne, E., Ellis, V. & Dano, K. (1991b) The receptor for urokinase type plasminogen activator (u-PAR) has a glycolipid membrane anchor and is deficient in paroxysmal nocturnal haemoglobinuria. (Abstract). Thrombosis and Haemostasis, 65, 683. Pollanen, J., Hedman, K., Nielsen, D. S., Dano, K. & Vaheri, A. (1988) Ultrastructural localization of plasma membrane-associated urokinase-type plasminogen activator at focal contacts. Journal of Cell Biology, 106, 87–95. Pollanen, J., Saksela, O., Salonen, E. M., Andreasen, P., Nielsen, L., Dano, K. & Vaheri, A. (1987) Distinct localizations of urokinase type plasminogen activator and its type 1 inhibitor under cultures of human fibroblasts and sarcoma cells. Journal of Cell Biology, 104, 1085–1096. Quax, P. H. A., van der Hoogen, M., Verheijen, J. H., Padro, T., Zeheb, R., Gelehrter T. D., Van Berkel, T. J. C., Kuiper, J. & Emeis, J. J. (1990a) Endotoxin induction of plasminogen activator and plasminogen activator inhibitor type 1 mRNA in rat tissue in vivo. Journal of Biological Chemistry, 265, 15560–15563. Quax, P. H. A., Van Leeuwen, R. T. J., Verspaget, H. W. & Verheijen, J. H. (1990b) Protein and messenger RNA levels of plasminogen activators and inhibitors analyzed in 22 human tumour cell lines. Cancer Research, 50, 1488–1494. Ramakrishan, V., Sinicropi, D. V., Dere, R., Darbonne, W. C., Bechtol, K. B. & Baker, J. B. (1990) The interaction of wild-type and catalytically inactive forms of tissue-type plasminogen activator with human umbilical vein endothelial cell monolayers. Journal of Biological Chemistry, 265, 2755–2762. Saksela, O. (1985) Plasminogen activation and regulation of pericellular proteolysis. Biochimica et Biophysica Acta, 823, 35–65. Saksela, O. & Rifkin, D. B. (1988) Cell-associated plasminogen activation: regulation and physiological functions. Annual Reviews in Cell Biology, 4, 93–126. Sappino, A. P., Huarte, J., Belin, D. & Vassalli, J. D. (1989) Plasminogen activation in tissue remodelling and invasion: mRNA localization in mouse ovaries and implanting embryos. Journal of Cell Biology, 109, 2471–2479. Sappino, A. P., Huarte, J., Vassalli, J-D. & Belin, D. (1991) Sites of synthesis of urokinase and tissue type plasminogen activator in the murine kidney. Journal of Clinical Investigation, 87, 962–970. Sato, Y. & Rifkin, D. B. (1988) Autocrine activities of basic fibroblast growth factor. Regulation of endothelial cell movement, plasminogen activator synthesis and DNA synthesis. Journal of Cell Biology, 107, 1199–1205. Sato, Y., Tsuboi, R., Lyons, R., Moses, H. & Rifkin, D. B. (1990) Characterization of the activator of latent TGF-beta by cocultures of endothelial cells and pericytes or smooth muscle cells: a self regulating system. Journal of Cell Biology, 111, 757–763. Seeds, N. W., Verrall, S., Glenn, F., Gadotti, D. & McGuire, P. G. (1991) Plasminogen activator and PA-receptors during neural development. (Abstract). Thrombosis and Haemostasis, 65, 686. Stoppelli, M. P., Corti, A., Soffientini, A., Cassani, G., Blasi, F. & Associan, R. K. (1985) Differentiation-enhanced binding of the amino-terminal fragment of human urokinase plasminogen activator to a specific receptor on U937 monocytes. Proceedings of the National Academy of Sciences of the United States of America, 82, 4939–4943. Strickland, S., Huarte, J., Belin, D., Vassalli, A., Richles, R. J. & Vassalli, J. D. (1988) Antisense RNA directed against the 3′ non-coding region prevents dormant mRNA activation in mouse oocytes. Science, 241, 680–684. Takada, A., Sakakibara, K., Nagase, M., Shigume, K. & Takada, Y. (1986) Determinants of urokinase in the urine of healthy volunteers and patients with renal diseases. Thrombosis Research, 44, 867–873. Tate, K. M., Higgins, D. L., Holmes, W. E., Winkler, M. E., Heyneker, K. L. & Vehar, G. A. (1987) Functional role of proteolytic cleavage at Arginine-275 of human tissue plasminogen activator as assessed by site-directed mutagenesis. Biochemistry, 26, 338–343. Vassalli, J. D., Baccino, D. & Belin, D. (1985) A cellular binding site for the Mr 55,000 form of the human plasminogen activator, urokinase. Journal of Cell Biology, 100, 86–92. Vihko, K. H., Penttila, T. L., Parvinnen, M. & Belin, D. (1989) Regulation of urokinase and tissue-type plasminogen activator gene expression in the rat seminiferous epithelium. Molecular Endocrinology, 3, 52–59. Wallen, P. (1987) Structure and function of tissue plasminogen activator and urokinase. Fundamental and Clinical Fibrinolysis (ed. by F. J. Castellino, P. J. Gaffney, M. M. Samama and A. Takada), pp. 1–19. Excerpta Medica, Amsterdam . Wittrup, M., Plesner, T., Ploug, U., Ronne, E., Dano, K., Johnsen, H., Carlsen, K., Kjaerrgaard, E. & Gram, J. (1991) Expression of u-PAR in acute myeloid leukemic, acute and chronic lymphocyte leukemia and non-Hodgkins lymphoma. 3rd International Workshop on Molecular and Cellular Biology of Plasminogen Activation, Elsinore, Denmark, May 1991, Abstract 172. Citing Literature Volume79, Issue4December 1991Pages 537-543 ReferencesRelatedInformation
Referência(s)