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Molecular components of the adherens junction

2008; Elsevier BV; Volume: 1778; Issue: 3 Linguagem: Inglês

10.1016/j.bbamem.2007.12.015

1879-2642

Carien M. Niessen, Cara J. Gottardi,

Cancer-related gene regulation

Adherens junctions serve to couple individual cells into various arrangements required for tissue structure and function. The central structural components of adherens junctions are transmembrane adhesion receptors, and their associated actin-binding/regulatory proteins. The molecular machineries that organize these adhesion receptor complexes into higher order junction structures, and the functional consequences of this junctional organization will be discussed.