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Natural exposure and serum antibodies to house dust mite of mite-allergic children with asthma in Atlanta

1985; Elsevier BV; Volume: 76; Issue: 6 Linguagem: Inglês

10.1016/0091-6749(85)90748-1

1097-6825

Thomas J. Smith, Libby A. Kelly, Peter W. Heymann, S WILKINS, Thomas A.E. Platts‐Mills,

Allergic Rhinitis and Sensitization

Pyoglyphidmites in house dusr arc itnportanr allcr~ens as.sociutud with asthma in Europe.hur comparable srudies of house dust mites in the home.s of patients bvirh asrhma have trot been dotw in the United Stutcs.We examined the distriburion of mire.\ and tnitr aller,~en in the houcr of' 20 mite-sensitive childrrn rt?fh asrhtna in Atlanta and tneaswrd f,yyE antibodie.\to ttrite allrr,yms in their sent.One or more dust samples Jktm bedding.brdroom jlwr, tele~~ision room ,florv.or rrlel2ision room jirrtiiturc~ /km 171-70 house.~cwilained 2 IO.000 n,q cf/ cinri,qi~n P eyuivalenr per jyatn i!f,fitzu dust; aniixmIs rangedJrom 1380 trt 30.400 n,ql.qvn.Allqytt lewl.5 I,'cre higher in dast samplc,~ ,frotn ,/itrnitrrre and htdclin,y tizm Jirotn ,fhm Du.\I samplr.\obrainrd fkom houses in June to Septprrwbur htrd more mites and mite trllcr~yrtt than thnsc housc.~.strmpled in March to April; relari\*c, humidi& in the room also MYIS hi,rhrr in June to September.Mite tiutnher.sand allcr,yen in jloor and ,fiaxiture satnpks xvrc cvrrclated \cirh re1arii.chumidi itt the room and were high vvhett t-elatirse hutnidi~~ NU.S :301ii : trtiri~~~~~n I', equi\,ctlrtrr wt., :; tO.000 nglgtn in Z//39 .YIK#Z .wtnpks.Dermatophagoides pteronyssinus ,\u.s prewttf in all houses and dominunt in I I/170.II.farinac ~t'as found in I7 hous~~.sand wtt.s dotnittatt~ tn si.\.Ail c.hildren .srudiedhad high IgE anriboc!\ with either 0. t'arinae ctr U. pteronyssinus KAST: I6 of the 10 children also had I# to anf&~tt P,.It is likely that rhc I,qE atttrbocl~ rc~sp:~n~e,~ tn kso '0 (4tildren with asthma were a dirc,c.tresult of et-lxt.surc to high lc~~~l.so/ ttritc rtllrrgctt.WC ~\peculote that rhc mite setlsitivi~~ I$ rhrse children mighr p/a\, 11 ctrusctti~~c~ role in their asthma.Thc.sr rexuks al.so .