Creutzfeldt–Jakob disease associated with cadaveric dura mater grafts in Japan
2000; Lippincott Williams & Wilkins; Volume: 55; Issue: 5 Linguagem: Inglês
10.1212/wnl.55.5.718
ISSN1526-632X
AutoresK. Hoshi, Hiide Yoshino, Jungo Urata, Yosikazu Nakamura, Hiroshi Yanagawa, Takeshi Sato,
Tópico(s)Alcoholism and Thiamine Deficiency
ResumoArticle abstract A nationwide survey and recent information documented 57 patients with Creutzfeldt–Jakob disease (CJD) who had received dura mater grafts during the period between January 1979 and September 1999. At least 54 of these 57 patients received the same brand of dura mater graft from the same processor. Mean age at disease onset in the 57 patients with dural grafts was younger (51.9 years) than that in patients with sporadic CJD (63 years) ( p < 0.0001). Initial symptoms were cerebellar ataxia, disorientation, and visual or oculomotor disturbance.
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