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The Rationale for Glutamate Antagonists in the Treatment of Traumatic Brain Injury

1995; Wiley; Volume: 765; Issue: 1 Linguagem: Inglês

10.1111/j.1749-6632.1995.tb16583.x

1749-6632

John S. Myseros, R. Morris Bullock,

Anesthesia and Neurotoxicity Research

Annals of the New York Academy of SciencesVolume 765, Issue 1 p. 262-271 The Rationale for Glutamate Antagonists in the Treatment of Traumatic Brain Injury J. S. MYSEROS, J. S. MYSEROS Division of Neurosurgery MCV Station Box 980631 Richmond, Virginia 23298–0631Search for more papers by this authorR. BULLOCK, R. BULLOCK Division of Neurosurgery MCV Station Box 980631 Richmond, Virginia 23298–0631Search for more papers by this author J. S. MYSEROS, J. S. MYSEROS Division of Neurosurgery MCV Station Box 980631 Richmond, Virginia 23298–0631Search for more papers by this authorR. BULLOCK, R. BULLOCK Division of Neurosurgery MCV Station Box 980631 Richmond, Virginia 23298–0631Search for more papers by this author First published: September 1995 https://doi.org/10.1111/j.1749-6632.1995.tb16583.xCitations: 23AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat REFERENCES 1 Blumberg, P. C., N. R. Jones & J. B. North. 1989. Diffuse axonal injury in head trauma. J. Neurol. Neurosurg. Psychiatry 52: 838–842. 2 Becker, D. P., Y. Katayama, T. Tamura, L. Gorman & M. K. Cheung. 1989. 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Blackwell Scientific. London . 33 McIntosh, T. K., R. Vink, H. Soares, R. Hayes & R. Simon. 1990. Effect of noncompetitive blockade of N-methyl-d-aspartate receptors on the neurochemical sequelae of experimental brain injury. J. Neurochem. 55: 1170–1179. 34 Shapira Y., G. Yadid, S. Cotev, A. Niska & E. Shohami. 1990. Protective effect of MK801 in experimental brain injury. J. Neurotrauma 7: 131–139. 35 Hayes, R. L., L. W. Jenkins, B. G. Lyeth, R. L. Balster, S. E. Robinson, G. L. Clifton, J. F. Stubbins & H. F. Young. 1988. Pretreatment with phencyclidine, an N-methyl-d-aspartate antagonist, attenuates long-term behavioral deficits in the rat produced by traumatic brain injury. J. Neurotrauma 5: 259–274. 36 Jenkins, L. W., B. G. Lyeth, W. Lewelt, K. Moszynski, D. S. Dewitt, R. L. Balster, L. P. Miller, G. L. Clifton, H. F. Young & R. L. Hayes. 1988. Combined pretrauma scopolamine and phencyclidine attenuates posttraumatic increased sensitivity to delayed secondary ischemia. J. Neurotrauma 5: 275–287. 37 McIntosh, T. K., R. Vink, H. Soares, R. Hayes & R. Simon. 1989. Effects of the N-methyl-d-aspartate receptor blocker MK-801 on neurologic function after experimental brain injury. J. Neurotrauma 6: 247–259. 38 McIntosh, T. K., R. Vink, I. Yamakami & A. I. Faden. Magnesium protects against neurological deficit after brain injury. Brain Res. 482: 252–260. 39 Lyeth, B. G., L. W. Jenkins, R. J. Hamm, L. L. Phillips, C. E. Dixon, H. F. Young, J. F. Stubbins, G. L. Clifton & R. L. Hayes. 1989. Pretreatment with MK-801 reduces behavioral deficits following traumatic brain injury (TBI) in rats. Soc. Neurosci. Abstr. 15: 1113. 40 Hamm, R. J., D. M. O'dell, B. R. Pike & B. G. Lyeth. 1993. Cognitive impairment following traumatic brain injury: the effect of pre- and postinjury administration of scopolamine and MK-801. J. Cognit. Brain Res. 1: 223–226, 1993. 41 Smith, D. H., K. Okiyama, M. Thomas, B. Nolan & T. K. McIntosh. 1991. The effects of two novel NMDA antagonists on regional cation concentration and edema formation following experimental brain injury. J. Cereb. Blood Flow Metab. 11(Suppl. 2): S 300. 42 Smith, D. H., M. Thomas, H. Soares & T. K. McIntosh. 1990. Differential effects of competitive and non-competitive N-methyl-d-aspartate (NMDA) receptor antagonists in experimental brain injury. FASEB J. 4: 773. 43 Smith, D. H., K. Okiyama & T. K. McIntosh. 1991. Ketamine and magnesium attenuate memory loss after experimental brain injury. Soc. Neurosci. Abstr. 17: 167. 44 Smith, D. H., K. Okiyama, M. Thomas & T. K. McIntosh. 1990. An NMDA receptor-associated glycine site antagonist attenuates memory loss after experimental brain injury. Soc. Neurosci. Abstr. 2: 779. Citing Literature Volume765, Issue1Neuroprotective Agents: Clinical and Experimental AspectsSeptember 1995Pages 262-271 ReferencesRelatedInformation