Asymmetric reduction of prochiral aromatic ketones by Borane–Amine complexes in the presence of a chiral amine–BF 3 catalyst
1990; Royal Society of Chemistry; Issue: 17 Linguagem: Inglês
10.1039/c39900001145
ISSN2050-5639
AutoresJ. V. Bhaskar Kanth, Mariappan Periasamy,
Tópico(s)Surface Chemistry and Catalysis
ResumoThe (–)-N-α-Methylbenzyl-3,5-dihydrodinaphthazepine–BH3 complex reduces aromatic ketones to alcohols with 11–57% enantiomeric excess (e.e.) in the presence of BF3·OEt2, the (–)-N-α-methylbenzyl-3,5 dihydrodinaphthazepine–BF3 complex catalyses asymmetric reduction of acetophenone by N,N′-diethylaniline–BH3 to give α-phenylethyl alcohol in 51% e.e.
Referência(s)