Triglyceride synthesis: insights from the cloning of diacylglycerol acyltransferase
2000; Lippincott Williams & Wilkins; Volume: 11; Issue: 3 Linguagem: Inglês
10.1097/00041433-200006000-00002
ISSN1473-6535
AutoresRobert V. Farese, Sylvaine Cases, Steven J. Smith,
Tópico(s)Microbial Metabolic Engineering and Bioproduction
ResumoAlthough the biochemistry of triglyceride synthesis has been studied for decades, an understanding of the molecular processes involved has been lacking. The recent cloning of a gene encoding acyl coenzyme A : diacylglycerol acyltransferase, an enzyme that catalyses the final step in triglyceride synthesis, has opened this area to molecular investigation and has begun to provide new insights into triglyceride metabolism.
Referência(s)