The uptake of tritiated oestradiol and oestrone by the uterus of the ovariectomised mouse following local application
1964; Elsevier BV; Volume: 3; Issue: 6 Linguagem: Inglês
10.1016/0039-128x(64)90118-7
ISSN1878-5867
Autores Tópico(s)Effects and risks of endocrine disrupting chemicals
ResumoThe uptake of tritiated oestradiol and oestrone by the uterus of the ovariectomised mouse has been studied following local application. With both compounds there was a peak in tissue radioactivity approximately 1 minute after application followed by a steady decline over the next 12 hours. The rate of decrease in activity was more rapid with oestrone than with oestradiol and may explain the lower biological activity of oestrone in local tests.
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