Novel Polyelectrolyte Carboxymethyl Konjac Glucomannan–Chitosan Nanoparticles for Drug Delivery
2004; Wiley; Volume: 25; Issue: 9 Linguagem: Inglês
10.1002/marc.200300314
ISSN1521-3927
AutoresJian Du, Rui Sun, Sheng Zhang, Thirumala Govender, Lifang Zhang, Chengdong Xiong, Yuxing Peng,
Tópico(s)Proteins in Food Systems
ResumoAbstract Summary: Carboxymethyl Konjac Glucomannan–Chitosan (CKGM‐CS) nanoparticles, which are well dispersed and stable in aqueous solution, were spontaneously prepared under very mild conditions by polyelectrolyte complexation. Investigations of the physicochemical properties of these nanoparticles were undertaken. This study showed that the nanoparticulate system driven by complex formation has potential as an advanced drug‐delivery system for water‐soluble drugs. Preparation mechanism of CS–CKGM nanoparticles. image Preparation mechanism of CS–CKGM nanoparticles.
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