Portal de Periódicos da CAPES

Capillary electrophoresis–electrochemistry microfluidic system for the determination of organic peroxides

2002; Elsevier BV; Volume: 952; Issue: 1-2 Linguagem: Inglês

10.1016/s0021-9673(02)00075-4

1873-3778

Joseph Wang, Alberto Escarpa, Martin Pumera, Jason Feldman,

Electrochemical Analysis and Applications

A microfluidic analytical system for the separation and detection of organic peroxides, based on a microchip capillary electrophoresis device with an integrated amperometric detector, was developed. The new microsystem relies on the reductive detection of both organic acid peroxides and hydroperoxides at −700 mV (vs. Ag wire/AgCl). Factors influencing the separation and detection processes were examined and optimized. The integrated microsystem offers rapid measurements (within 130 s) of these organic-peroxide compounds, down to micromolar levels. A highly stable response for repetitive injections (RSD 0.35–3.12%; n=12) reflects the negligible electrode passivation. Such a “lab-on-a-chip” device should be attractive for on-site analysis of organic peroxides, as desired for environmental screening and industrial monitoring.