Artigo Revisado por pares

Phytoecdysteroids from Ajuga macrosperma var. breviflora Roots

2008; American Chemical Society; Volume: 71; Issue: 7 Linguagem: Inglês

10.1021/np800131f

ISSN

1520-6025

Autores

Amaya Castro, Josep Coll, Yudelsy A. Tandrón, Anil K. Pant, C. S. Mathela,

Tópico(s)

Phytochemistry and Biological Activities

Resumo

Three new phytoecdysteroids, ajugacetalsterones C (1) and D (3) and breviflorasterone (2), were isolated from the roots of Ajuga macrosperma var. breviflora along with five known compounds, namely, 20-hydroxyecdysone, cyasterone, makisterone A, 20-hydroxyecdysone 3-acetate, and 20-hydroxyecdysone 2-acetate. The structures of 1−3 were elucidated on the basis of extensive 1D and 2D NMR spectroscopic studies. The new compounds possess acetal oxygen bridges between C-26 and C-20/C-22, or C-26/C-23, or a lactone bridge between C-26 and C-23.

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