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Artigo Acesso aberto Revisado por pares
BIBTEX RIS

Carbon Monoxide Protects against Ventilator-induced Lung Injury via PPAR-γ and Inhibition of Egr-1

2008; American Thoracic Society; Volume: 177; Issue: 11 Linguagem: Inglês

10.1164/rccm.200708-1265oc

ISSN

1535-4970

Autores

Alexander Hoetzel, Tamás Dolinay, Simone Vallbracht, Yingze Zhang, Hong Pyo Kim, Emeka Ifedigbo, Sean Alber, A. Murat Kaynar, René Schmidt, Stefan W. Ryter, Augustine M.K. Choi,

Tópico(s)

Respiratory Support and Mechanisms

Resumo

Ventilator-induced lung injury (VILI) leads to an unacceptably high mortality. In this regard, the antiinflammatory properties of inhaled carbon monoxide (CO) may provide a therapeutic option.

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