Portal de Periódicos da CAPES

Papain‐like cysteine proteases: key players at molecular battlefields employed by both plants and their invaders

2007; Wiley; Volume: 9; Issue: 1 Linguagem: Inglês

10.1111/j.1364-3703.2007.00439.x

1464-6722

Takayuki Shindo, Renier A. L. van der Hoorn,

Studies on Chitinases and Chitosanases

ABSTRACT Papain‐like cysteine proteases (PLCPs) play crucial roles in plant–pathogen/pest interactions. During these parasitic interactions, PLCPs act on non‐self substrates, provoking the selection of counteracting inhibitors and other means to evade proteolysis. We review examples of PLCPs acting on molecular battlefields in the extracellular space, plant cytoplasm and herbivore gut. Examples are maize Mir1 ( M aize i nbred r esistance 1 ), tomato Rcr3 ( R equired for C ladosporium r esistance‐ 3 ), Pseudomonas AvrRpt2 and AurPphB, insect DvCAL1 ( D iabrotica v irgifera c athepsin L ‐like p rotease‐ 1 ) and nematode MiCpl1 ( M eloidogyne i ncognita c athepsin L ‐like p rotease 1 ). The data suggest that PLCPs cleave specific proteins and that their translocation, activation and inhibition of PLCPs are tightly regulated.