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Recent developments in supercritical fluid chromatography-mass spectrometry coupling

1995; Elsevier BV; Volume: 703; Issue: 1-2 Linguagem: Inglês

10.1016/0021-9673(95)00123-5

1873-3778

Patrick Arpino, P. Haas,

Advanced Chemical Sensor Technologies

After some time of stagnation, research in supercritical fluid chromatography (SFC)-mass spectrometry (MS) coupling has been recently revived by investigations into the use of atmospheric pressure ionisation (API) techniques. Following a short introduction into the historical development, the present state of the art in SFC and the actual trends in the field of SFC-MS, the different interfacing methods are presented briefly discussing its advantages and drawbacks. Special attention is given to new results and recent developments including a survey of applications reported during the last few years.