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Can Hemophilic Patients Be Adequately Maintained with Cryoprecipitates? Or Is it Desirable or Even Necessary to Manufacture and Administer Highly Concentrated AHF Products?

1972; Wiley; Volume: 22; Issue: 6 Linguagem: Inglês

10.1111/j.1423-0410.1972.tb04646.x

1423-0410

Rosemary Biggs, K. M. Brinkhous, Andrew E. Weiss, A. H. F. Britten, Katharine, M. Dormandy, J. van der Meer, Inga Marie Nilsson, Edward Shanbrom,

Coagulation, Bradykinin, Polyphosphates, and Angioedema

Vox SanguinisVolume 22, Issue 6 p. 554-565 Can Hemophilic Patients Be Adequately Maintained with Cryoprecipitates? Or Is it Desirable or Even Necessary to Manufacture and Administer Highly Concentrated AHF Products? Dr. Rosemary Biggs, Corresponding Author Dr. Rosemary Biggs Oxford Haemophilia Centre, Churchill Hospital, Headington, Oxford, OX3 7LJ (England) University of North Carolina, School of Medicine, Department of Pathology, Chapel Hill, NC 27515 (USA) New England Medical Center Hospitals, Blood Coagulation Laboratory, 171 Harrison Avenue, Boston, MA 02111 (USA) Haemophilia Centre, The Royal Free Hospital, Lawn Road, London, NW 3 (England) Central Laboratory, Blood Transfusion Service, P.O. Box 9190, Amsterdam-W (Netherlands) Coagulation Laboratory, Allmänna Sjukhuset, S-214 01 Malmö (Sweden) Hyland, Division Travenol Laboratories, P.O. Box 2214, Costa Mesa, CA 92626 (USA)Search for more papers by this authorDr. K. M. Brinkhous, Corresponding Author Dr. K. M. Brinkhous Oxford Haemophilia Centre, Churchill Hospital, Headington, Oxford, OX3 7LJ (England) University of North Carolina, School of Medicine, Department of Pathology, Chapel Hill, NC 27515 (USA) New England Medical Center Hospitals, Blood Coagulation Laboratory, 171 Harrison Avenue, Boston, MA 02111 (USA) Haemophilia Centre, The Royal Free Hospital, Lawn Road, London, NW 3 (England) Central Laboratory, Blood Transfusion Service, P.O. Box 9190, Amsterdam-W (Netherlands) Coagulation Laboratory, Allmänna Sjukhuset, S-214 01 Malmö (Sweden) Hyland, Division Travenol Laboratories, P.O. Box 2214, Costa Mesa, CA 92626 (USA)Search for more papers by this authorDr. A. E. Weiss, Corresponding Author Dr. A. E. Weiss Oxford Haemophilia Centre, Churchill Hospital, Headington, Oxford, OX3 7LJ (England) University of North Carolina, School of Medicine, Department of Pathology, Chapel Hill, NC 27515 (USA) New England Medical Center Hospitals, Blood Coagulation Laboratory, 171 Harrison Avenue, Boston, MA 02111 (USA) Haemophilia Centre, The Royal Free Hospital, Lawn Road, London, NW 3 (England) Central Laboratory, Blood Transfusion Service, P.O. Box 9190, Amsterdam-W (Netherlands) Coagulation Laboratory, Allmänna Sjukhuset, S-214 01 Malmö (Sweden) Hyland, Division Travenol Laboratories, P.O. Box 2214, Costa Mesa, CA 92626 (USA)Search for more papers by this authorDr. A. H. F. Britten, Corresponding Author Dr. A. H. F. Britten Oxford Haemophilia Centre, Churchill Hospital, Headington, Oxford, OX3 7LJ (England) University of North Carolina, School of Medicine, Department of Pathology, Chapel Hill, NC 27515 (USA) New England Medical Center Hospitals, Blood Coagulation Laboratory, 171 Harrison Avenue, Boston, MA 02111 (USA) Haemophilia Centre, The Royal Free Hospital, Lawn Road, London, NW 3 (England) Central Laboratory, Blood Transfusion Service, P.O. Box 9190, Amsterdam-W (Netherlands) Coagulation Laboratory, Allmänna Sjukhuset, S-214 01 Malmö (Sweden) Hyland, Division Travenol Laboratories, P.O. Box 2214, Costa Mesa, CA 92626 (USA)Search for more papers by this authorDr. Katharine, Corresponding Author Dr. Katharine Oxford Haemophilia Centre, Churchill Hospital, Headington, Oxford, OX3 7LJ (England) University of North Carolina, School of Medicine, Department of Pathology, Chapel Hill, NC 27515 (USA) New England Medical Center Hospitals, Blood Coagulation Laboratory, 171 Harrison Avenue, Boston, MA 02111 (USA) Haemophilia Centre, The Royal Free Hospital, Lawn Road, London, NW 3 (England) Central Laboratory, Blood Transfusion Service, P.O. Box 9190, Amsterdam-W (Netherlands) Coagulation Laboratory, Allmänna Sjukhuset, S-214 01 Malmö (Sweden) Hyland, Division Travenol Laboratories, P.O. Box 2214, Costa Mesa, CA 92626 (USA)Search for more papers by this authorM. Dormandy, Corresponding Author M. Dormandy Oxford Haemophilia Centre, Churchill Hospital, Headington, Oxford, OX3 7LJ (England) University of North Carolina, School of Medicine, Department of Pathology, Chapel Hill, NC 27515 (USA) New England Medical Center Hospitals, Blood Coagulation Laboratory, 171 Harrison Avenue, Boston, MA 02111 (USA) Haemophilia Centre, The Royal Free Hospital, Lawn Road, London, NW 3 (England) Central Laboratory, Blood Transfusion Service, P.O. Box 9190, Amsterdam-W (Netherlands) Coagulation Laboratory, Allmänna Sjukhuset, S-214 01 Malmö (Sweden) Hyland, Division Travenol Laboratories, P.O. Box 2214, Costa Mesa, CA 92626 (USA)Search for more papers by this authorDr. J. van der Meer, Corresponding Author Dr. J. van der Meer Oxford Haemophilia Centre, Churchill Hospital, Headington, Oxford, OX3 7LJ (England) University of North Carolina, School of Medicine, Department of Pathology, Chapel Hill, NC 27515 (USA) New England Medical Center Hospitals, Blood Coagulation Laboratory, 171 Harrison Avenue, Boston, MA 02111 (USA) Haemophilia Centre, The Royal Free Hospital, Lawn Road, London, NW 3 (England) Central Laboratory, Blood Transfusion Service, P.O. Box 9190, Amsterdam-W (Netherlands) Coagulation Laboratory, Allmänna Sjukhuset, S-214 01 Malmö (Sweden) Hyland, Division Travenol Laboratories, P.O. Box 2214, Costa Mesa, CA 92626 (USA)Search for more papers by this authorProf. Dr. Inga Marie Nilsson, Corresponding Author Prof. Dr. Inga Marie Nilsson Oxford Haemophilia Centre, Churchill Hospital, Headington, Oxford, OX3 7LJ (England) University of North Carolina, School of Medicine, Department of Pathology, Chapel Hill, NC 27515 (USA) New England Medical Center Hospitals, Blood Coagulation Laboratory, 171 Harrison Avenue, Boston, MA 02111 (USA) Haemophilia Centre, The Royal Free Hospital, Lawn Road, London, NW 3 (England) Central Laboratory, Blood Transfusion Service, P.O. Box 9190, Amsterdam-W (Netherlands) Coagulation Laboratory, Allmänna Sjukhuset, S-214 01 Malmö (Sweden) Hyland, Division Travenol Laboratories, P.O. Box 2214, Costa Mesa, CA 92626 (USA)Search for more papers by this authorDr. Edward Shanbrom, Corresponding Author Dr. Edward Shanbrom Oxford Haemophilia Centre, Churchill Hospital, Headington, Oxford, OX3 7LJ (England) University of North Carolina, School of Medicine, Department of Pathology, Chapel Hill, NC 27515 (USA) New England Medical Center Hospitals, Blood Coagulation Laboratory, 171 Harrison Avenue, Boston, MA 02111 (USA) Haemophilia Centre, The Royal Free Hospital, Lawn Road, London, NW 3 (England) Central Laboratory, Blood Transfusion Service, P.O. Box 9190, Amsterdam-W (Netherlands) Coagulation Laboratory, Allmänna Sjukhuset, S-214 01 Malmö (Sweden) Hyland, Division Travenol Laboratories, P.O. Box 2214, Costa Mesa, CA 92626 (USA)Search for more papers by this author Dr. Rosemary Biggs, Corresponding Author Dr. Rosemary Biggs Oxford Haemophilia Centre, Churchill Hospital, Headington, Oxford, OX3 7LJ (England) University of North Carolina, School of Medicine, Department of Pathology, Chapel Hill, NC 27515 (USA) New England Medical Center Hospitals, Blood Coagulation Laboratory, 171 Harrison Avenue, Boston, MA 02111 (USA) Haemophilia Centre, The Royal Free Hospital, Lawn Road, London, NW 3 (England) Central Laboratory, Blood Transfusion Service, P.O. Box 9190, Amsterdam-W (Netherlands) Coagulation Laboratory, Allmänna Sjukhuset, S-214 01 Malmö (Sweden) Hyland, Division Travenol Laboratories, P.O. Box 2214, Costa Mesa, CA 92626 (USA)Search for more papers by this authorDr. K. M. Brinkhous, Corresponding Author Dr. K. M. Brinkhous Oxford Haemophilia Centre, Churchill Hospital, Headington, Oxford, OX3 7LJ (England) University of North Carolina, School of Medicine, Department of Pathology, Chapel Hill, NC 27515 (USA) New England Medical Center Hospitals, Blood Coagulation Laboratory, 171 Harrison Avenue, Boston, MA 02111 (USA) Haemophilia Centre, The Royal Free Hospital, Lawn Road, London, NW 3 (England) Central Laboratory, Blood Transfusion Service, P.O. Box 9190, Amsterdam-W (Netherlands) Coagulation Laboratory, Allmänna Sjukhuset, S-214 01 Malmö (Sweden) Hyland, Division Travenol Laboratories, P.O. Box 2214, Costa Mesa, CA 92626 (USA)Search for more papers by this authorDr. A. E. Weiss, Corresponding Author Dr. A. E. Weiss Oxford Haemophilia Centre, Churchill Hospital, Headington, Oxford, OX3 7LJ (England) University of North Carolina, School of Medicine, Department of Pathology, Chapel Hill, NC 27515 (USA) New England Medical Center Hospitals, Blood Coagulation Laboratory, 171 Harrison Avenue, Boston, MA 02111 (USA) Haemophilia Centre, The Royal Free Hospital, Lawn Road, London, NW 3 (England) Central Laboratory, Blood Transfusion Service, P.O. Box 9190, Amsterdam-W (Netherlands) Coagulation Laboratory, Allmänna Sjukhuset, S-214 01 Malmö (Sweden) Hyland, Division Travenol Laboratories, P.O. Box 2214, Costa Mesa, CA 92626 (USA)Search for more papers by this authorDr. A. H. F. Britten, Corresponding Author Dr. A. H. F. Britten Oxford Haemophilia Centre, Churchill Hospital, Headington, Oxford, OX3 7LJ (England) University of North Carolina, School of Medicine, Department of Pathology, Chapel Hill, NC 27515 (USA) New England Medical Center Hospitals, Blood Coagulation Laboratory, 171 Harrison Avenue, Boston, MA 02111 (USA) Haemophilia Centre, The Royal Free Hospital, Lawn Road, London, NW 3 (England) Central Laboratory, Blood Transfusion Service, P.O. Box 9190, Amsterdam-W (Netherlands) Coagulation Laboratory, Allmänna Sjukhuset, S-214 01 Malmö (Sweden) Hyland, Division Travenol Laboratories, P.O. Box 2214, Costa Mesa, CA 92626 (USA)Search for more papers by this authorDr. Katharine, Corresponding Author Dr. Katharine Oxford Haemophilia Centre, Churchill Hospital, Headington, Oxford, OX3 7LJ (England) University of North Carolina, School of Medicine, Department of Pathology, Chapel Hill, NC 27515 (USA) New England Medical Center Hospitals, Blood Coagulation Laboratory, 171 Harrison Avenue, Boston, MA 02111 (USA) Haemophilia Centre, The Royal Free Hospital, Lawn Road, London, NW 3 (England) Central Laboratory, Blood Transfusion Service, P.O. Box 9190, Amsterdam-W (Netherlands) Coagulation Laboratory, Allmänna Sjukhuset, S-214 01 Malmö (Sweden) Hyland, Division Travenol Laboratories, P.O. Box 2214, Costa Mesa, CA 92626 (USA)Search for more papers by this authorM. Dormandy, Corresponding Author M. Dormandy Oxford Haemophilia Centre, Churchill Hospital, Headington, Oxford, OX3 7LJ (England) University of North Carolina, School of Medicine, Department of Pathology, Chapel Hill, NC 27515 (USA) New England Medical Center Hospitals, Blood Coagulation Laboratory, 171 Harrison Avenue, Boston, MA 02111 (USA) Haemophilia Centre, The Royal Free Hospital, Lawn Road, London, NW 3 (England) Central Laboratory, Blood Transfusion Service, P.O. Box 9190, Amsterdam-W (Netherlands) Coagulation Laboratory, Allmänna Sjukhuset, S-214 01 Malmö (Sweden) Hyland, Division Travenol Laboratories, P.O. Box 2214, Costa Mesa, CA 92626 (USA)Search for more papers by this authorDr. J. van der Meer, Corresponding Author Dr. J. van der Meer Oxford Haemophilia Centre, Churchill Hospital, Headington, Oxford, OX3 7LJ (England) University of North Carolina, School of Medicine, Department of Pathology, Chapel Hill, NC 27515 (USA) New England Medical Center Hospitals, Blood Coagulation Laboratory, 171 Harrison Avenue, Boston, MA 02111 (USA) Haemophilia Centre, The Royal Free Hospital, Lawn Road, London, NW 3 (England) Central Laboratory, Blood Transfusion Service, P.O. Box 9190, Amsterdam-W (Netherlands) Coagulation Laboratory, Allmänna Sjukhuset, S-214 01 Malmö (Sweden) Hyland, Division Travenol Laboratories, P.O. Box 2214, Costa Mesa, CA 92626 (USA)Search for more papers by this authorProf. Dr. Inga Marie Nilsson, Corresponding Author Prof. Dr. Inga Marie Nilsson Oxford Haemophilia Centre, Churchill Hospital, Headington, Oxford, OX3 7LJ (England) University of North Carolina, School of Medicine, Department of Pathology, Chapel Hill, NC 27515 (USA) New England Medical Center Hospitals, Blood Coagulation Laboratory, 171 Harrison Avenue, Boston, MA 02111 (USA) Haemophilia Centre, The Royal Free Hospital, Lawn Road, London, NW 3 (England) Central Laboratory, Blood Transfusion Service, P.O. Box 9190, Amsterdam-W (Netherlands) Coagulation Laboratory, Allmänna Sjukhuset, S-214 01 Malmö (Sweden) Hyland, Division Travenol Laboratories, P.O. Box 2214, Costa Mesa, CA 92626 (USA)Search for more papers by this authorDr. Edward Shanbrom, Corresponding Author Dr. Edward Shanbrom Oxford Haemophilia Centre, Churchill Hospital, Headington, Oxford, OX3 7LJ (England) University of North Carolina, School of Medicine, Department of Pathology, Chapel Hill, NC 27515 (USA) New England Medical Center Hospitals, Blood Coagulation Laboratory, 171 Harrison Avenue, Boston, MA 02111 (USA) Haemophilia Centre, The Royal Free Hospital, Lawn Road, London, NW 3 (England) Central Laboratory, Blood Transfusion Service, P.O. Box 9190, Amsterdam-W (Netherlands) Coagulation Laboratory, Allmänna Sjukhuset, S-214 01 Malmö (Sweden) Hyland, Division Travenol Laboratories, P.O. Box 2214, Costa Mesa, CA 92626 (USA)Search for more papers by this author First published: June 1972 https://doi.org/10.1111/j.1423-0410.1972.tb04646.xCitations: 4AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onFacebookTwitterLinkedInRedditWechat Citing Literature Volume22, Issue6June 1972Pages 554-565 RelatedInformation