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Erythrocytosis Associated With the Nephrotic Syndrome

1977; American Medical Association; Volume: 137; Issue: 8 Linguagem: Inglês

10.1001/archinte.1977.03630200070019

1538-3679

R. E. Sonneborn, Guido O. Pérez, Murray Epstein, Orlando J. Martelo, Victoriano Pardo,

Myeloproliferative Neoplasms: Diagnosis and Treatment

A 23-year-old man had true erythrocytosis and the nephrotic syndrome. A renal biopsy specimen showed focal sclerosing glomerulonephritis and nephrosclerosis. Both serum and urinary erythropoietin levels were increased, and plasma renin activity was in the high normal range. The association of erythrocytosis and glomerulonephritis with the nephrotic syndrome is reviewed, and the uniqueness of this association is proposed. Finally, a dissociation between these hormones was demonstrated using water immersion to the neck as a suppressive maneuver. ( Arch Intern Med 137:1068-1072, 1977)