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Neural pathogenesis of enterovirus 71 infection

2010; Elsevier BV; Volume: 12; Issue: 7 Linguagem: Inglês

10.1016/j.micinf.2010.03.006

1769-714X

Kuo‐Feng Weng, Li-Lien Chen, Peng-Nien Huang, Shin‐Ru Shih,

Viral gastroenteritis research and epidemiology

Enterovirus 71 (EV71) is a neurotropic pathogen that can cause severe neural diseases and complications on infected patients. Clinical observations showed that EV71-induced immune responses may be associated with virus induced neurogenic pulmonary edema. Here reviewed studies that discovered several host molecules as potential factors for EV71 virulence.