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Production of a radioactive 18F ion beam for nuclear reaction studies

1995; Elsevier BV; Volume: 103; Issue: 4 Linguagem: Inglês

10.1016/0168-583x(95)00657-5

1872-9584

Andrew D. Roberts, Robert J. Nickles, M. Paul, K. E. Rehm, C. L. Jiang, D. J. Blumenthal, J. Gehring, Deborah J. Henderson, J. A. Nolen, R. C. Pardo, J. P. Schiffer, R. E. Segel,

Nuclear Physics and Applications

A two-stage method for generating a radioactive 18F ion beam has been developed. 18F is produced with a medical cyclotron by 11 MeV proton activation of [18O]water, then chemically processed off-line for use in a tandem accelerator ion source. Azeotropic distillation reduces the 18O component by 105, with a resulting 18O to 18F beam ratio of about 103. The average 18F− beam intensity per synthesis is 1 ppA over 120 min from a cesium vapor, sputter negative ion source (SNICS), with a peak intensity of 4.5 ppA.