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Molecular genetics of sex determination in C. elegans

1992; Elsevier BV; Volume: 8; Issue: 5 Linguagem: Inglês

10.1016/0168-9525(92)90218-s

1362-4555

Patricia E. Kuwabara, Judith Kimble,

Circadian rhythm and melatonin

Sexual fate in the nematode Caenorhabditis elegans is controlled by a group of genetically well-characterized genes. Several of these sex-determining genes have now been analysed at the molecular level. Transcriptional regulation is likely to control both commitment to a single sexual fate and maintenance of that decision; in addition, intercellular signalling appears to coordinate the sexual fates of cells throughout the animal to adopt a single sexual fate.