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Artigo Revisado por pares
BIBTEX RIS

Subunit interaction in horse liver alcohol dehydrogenase: 35Cl nuclear magnetic resonance studies

1972; Elsevier BV; Volume: 257; Issue: 1 Linguagem: Inglês

10.1016/0005-2795(72)90267-x

ISSN

1878-1454

Autores

Björn Lindman, Michael Zeppezauer, Åke Åkeson,

Tópico(s)

Pancreatic function and diabetes

Resumo

Abstract From 35Cl NMR measurements it is shown that the initial identity of the subunits in coenzyme-free horse liver alcohol dehydrogenase (EC 1.1.1.1) disappears on addition of 1 mole of coenzyme. This experiment indicates an interaction between the protein chaines. Isobutyramide appears to affect the enzyme affinity for coenzyme binding.

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