Artigo Revisado por pares

Enantioselective synthesis of α-hydroxy phosphonates via oxidation with (camphorsulfonyl)oxaziridines

1997; Elsevier BV; Volume: 38; Issue: 20 Linguagem: Inglês

10.1016/s0040-4039(97)00705-3

ISSN

1873-3581

Autores

D. M. Pogatchnik, David F. Wiemer,

Tópico(s)

Synthesis and Catalytic Reactions

Resumo

Reaction of phosphonate anions with enantiomerically pure (camphorsulfonyl)oxaziridines results in formation of nonracemic α-hydroxy phosphonates. This enantioselective hydroxylation methodology provides convenient access to optically active α-hydroxy phosphonates and their corresponding phosphonic acids.

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