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Ones, Thiones, andN-Oxides: An Exercise in Imidazole Chemistry

2002; Wiley; Volume: 41; Issue: 13 Linguagem: Inglês

10.1002/1521-3773(20020703)41

1521-3773

Stefan Laufer, Gerd K. Wagner, Dunja Kotschenreuther,

Synthesis of heterocyclic compounds

Regioselective synthetic approaches to tetrasubstituted imidazoles (see picture) are reported. These highly substituted heterocycles are potent inhibitors of cytokine release and therefore interesting candidates for anti-inflammatory drugs. Supporting information for this article is available on the WWW under http://www.wiley-vch.de/contents/jc_2002/2002/z18173_s.pdf or from the author. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.