Portal de Periódicos da CAPES

Management of epilepsy associated with tuberous sclerosis complex (TSC): Clinical recommendations

2012; Elsevier BV; Volume: 16; Issue: 6 Linguagem: Inglês

10.1016/j.ejpn.2012.05.004

1532-2130

Paolo Curatolo, Sergiusz Jóźwiak, Rima Nabbout,

Tuberous Sclerosis Complex Research

Abstract Tuberous sclerosis complex (TSC) is a leading genetic cause of epilepsy. TSC-associated epilepsy generally begins during the first year of life, and is associated with neurodevelopmental and cognitive problems. Management is challenging and seizures tend to persist in a large proportion of patients despite pharmacological and surgical treatment. This report summarizes the clinical recommendations for the management of TSC-associated epilepsy made by a panel of European experts in March 2012. Current treatment options and outstanding questions are outlined.