Benzocaine and lidocaine induced methemoglobinemia after bronchoscopy: a case report
2008; BioMed Central; Volume: 2; Issue: 1 Linguagem: Inglês
10.1186/1752-1947-2-16
ISSN1752-1947
AutoresSophie Kwok, Jacqueline Fischer, John Rogers,
Tópico(s)Blood disorders and treatments
ResumoMethemoglobinemia is a rare cause of hypoxemia, characterized by abnormal levels of oxidized hemoglobin that cannot bind to and transport oxygen. A 62-year-old male underwent bronchoscopy where lidocaine oral solution and Hurricaine spray (20% benzocaine) were used. He developed central cyanosis and his oxygen saturation was 85% via pulse oximetry. An arterial blood gas revealed pH 7.45, PCO2 42, PO2 282, oxygen saturation 85%. Co-oximetry performed revealed a methemoglobin level of 17.5% (normal 0.6–2.5%). The patient was continued on 15 L/minute nonrebreathing face mask and subsequent oxygen saturation improved to 92% within two hours. With hemodynamic stability and improved SpO2, treatment with methylene blue was withheld. Methemoglobinemia is a potentially lethal condition after exposure to routinely used drugs. Physicians should be aware of this complication for early diagnosis and treatment.
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