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Gene Expression in Brain: A Window on Ethanol Dependence, Neuroadaptation, and Preference

2003; Wiley; Volume: 27; Issue: 2 Linguagem: Inglês

10.1097/01.alc.0000060101.89334.11

1530-0277

Paula L. Hoffman, Michael F. Miles, Howard J. Edenberg, Wolfgang H. Sommer, Boris Tabakoff, Jeanne M. Wehner, Joanne M. Lewohl,

Adipose Tissue and Metabolism

This article represents the proceedings of a symposium at the 2002 joint RSA/ISBRA Conference in San Francisco, California. The organizer was Paula L. Hoffman and the co-chairs were Paula L. Hoffman and Michael Miles. The presentations were (1) Introduction and overview of the use of DNA microarrays, by Michael Miles; (2) DNA microarray analysis of gene expression in brains of P and NP rats, by Howard J. Edenberg; (3) Gene expression patterns in brain regions of AA and ANA rats, by Wolfgang Sommer; (4) Patterns of gene expression in brains of selected lines of mice that differ in ethanol tolerance, by Boris Tabakoff; (5) Gene expression profiling related to initial sensitivity and tolerance in gamma-protein kinase C mutants, by Jeanne Wehner; and (6) Gene expression patterns in human alcoholic brain: from microarrays to protein profiles, by Joanne Lewohl.