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Synthesis of 3-indole derivatives by copper sulfonato Salen catalyzed three-component reactions in water

2011; Royal Society of Chemistry; Volume: 47; Issue: 13 Linguagem: Inglês

10.1039/c0cc05695b

1364-548X

Yanyang Qu, Fang Ke, Li Zhou, Zhengkai Li, Haifeng Xiang, Di Wu, Xiangge Zhou,

Chemical Synthesis and Reactions

An efficient three-component reaction of indole, aldehyde, and malononitrile in water catalyzed by a copper(II) sulfonato Salen complex afforded 3-indole derivatives in good to excellent yields up to 97%.