Artigo Revisado por pares

Simplified chromogenic substrate assay for low molecular weight heparin

1986; Elsevier BV; Volume: 42; Issue: 1 Linguagem: Inglês

10.1016/0049-3848(86)90202-1

ISSN

1879-2472

Autores

G.F. Handeland,

Tópico(s)

Proteoglycans and glycosaminoglycans research

Resumo

Chromogenic substrate (CS) assays for heparin in plasma (1,2,3, 4) are well suited for assay of LMW heparin when based on FXa inactivation. As CS assays tend to be complicated they are still not widely used in routine. This report concerns a simplified heparin assay based on a commercial kit. The standard curve is linear, and in the quick routine procedure two standards suffice Premade frozen standards further simplifies the assay, which has been easily introduced in a busy routine laboratory.

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