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Fibroin allergy. IgE mediated hypersensitivity to silk suture materials.

1999; Medknow; Volume: 66; Issue: 1 Linguagem: Inglês

10.1272/jnms.66.41

1884-0108

Sadayuki Kurosaki, Hirokuni Otsuka, Mayumi Kunitomo, Mamoru Koyama, Ruby Pawankar, Koshi Matumoto,

Contact Dermatitis and Allergies

Delayed-type hypersensitivity with granulomatous lesions to silk sutures is rather rate. Yet, braided silk sutures often act as a non-immunologic foreign-body and cause a granulomatous in-flammatory reaction years after surgery. We report here a case of recurrent granulomas with remarkable infiltration of eosinophils that may have resulted from an IgE-mediated hypersensitivity reaction to silk fibroin, a component of the braidid silk suture. Under normal circumstances exposure to fibroin is rather rare. Therefore, the present patient may have developed this reaction to the silk sutures used in a previous surgery. (J Nippon Med Sch 1999 ; 66 : 41-44)