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Imprinted polymers prepared by aqueous suspension polymerization

2000; Wiley; Volume: 77; Issue: 8 Linguagem: Inglês

10.1002/1097-4628(20000822)77

1097-4628

Asier Flores, David Cunliffe, Michael J. Whitcombe, Evgeny N. Vulfson,

Innovative Microfluidic and Catalytic Techniques Innovation

Journal of Applied Polymer ScienceVolume 77, Issue 8 p. 1841-1850 Imprinted polymers prepared by aqueous suspension polymerization Asier Flores, Asier Flores Institute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UKSearch for more papers by this authorDavid Cunliffe, David Cunliffe Institute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UKSearch for more papers by this authorMichael J. Whitcombe, Corresponding Author Michael J. Whitcombe [email protected] Institute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UKInstitute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UK===Search for more papers by this authorEvgeny N. Vulfson, Evgeny N. Vulfson Institute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UKSearch for more papers by this author Asier Flores, Asier Flores Institute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UKSearch for more papers by this authorDavid Cunliffe, David Cunliffe Institute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UKSearch for more papers by this authorMichael J. Whitcombe, Corresponding Author Michael J. Whitcombe [email protected] Institute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UKInstitute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UK===Search for more papers by this authorEvgeny N. Vulfson, Evgeny N. Vulfson Institute of Food Research, Norwich Research Park, Colney, Norwich, NR4 7UA, UKSearch for more papers by this author First published: 22 June 2000 https://doi.org/10.1002/1097-4628(20000822)77:8 3.0.CO;2-PCitations: 39Read the full textAboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Abstract The feasibility of preparing cholesterol-imprinted polymers by aqueous suspension polymerization was investigated by the preparation of ethyleneglycol dimethacrylate and divinylbenzene-based beads imprinted using cholesteryl(4-vinyl)phenyl carbonate as the template. A low volatility porogen to replace a 4:1 hexane/toluene mixture was selected on the basis of solubility parameters and consisted of dioctyl phthalate/n-decane 77:23 v/v. Beads were prepared using a range of porogen contents with the best results obtained at 5.5–6.5 mL /5 g of monomer. Uptake of cholesterol by suspension polymers was broadly similar to that of the corresponding “bulk” polymers, but suffered from higher nonspecific binding. © 2000 John Wiley & Sons, Inc. J Appl Polym Sci 77: 1841–1850, 2000 REFERENCES 1 Wulff, G. Angew Chem Intl Ed Engl 1995, 34, 1812. 10.1002/anie.199518121 CASWeb of Science®Google Scholar 2 Shea, K. 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