First trimester chorionic villi sampling and direct chromosome preparations
1986; Wiley; Volume: 29; Issue: 6 Linguagem: Inglês
10.1111/j.1399-0004.1986.tb00551.x
ISSN1399-0004
AutoresAvirachan T. Tharapel, John V. Dacus, Sugandhi A. Tharapel, John Dempsey, George S. Flinn, David C. Shaver, D Massouda, R. Sid Wilroy,
Tópico(s)Genomic variations and chromosomal abnormalities
ResumoChorionic villi sampling was performed on 52 patients prior to elective termination of their pregnancies. Villi were obtained in 42, and direct chromosome preparations were successful in 41 of them. The use of a mixture of 0.075 M potassium chloride and 1% sodium citrate in the ratio of 2:1 for hypotonic treatment and 40% acetic acid for cell dispersal yielded chromosomes with good morphology and G‐bands.
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