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Supersensitivity and Amine Oxidase Activity in Denervated Salivary Glands

1956; Wiley; Volume: 36; Issue: 1-2 Linguagem: Inglês

10.1111/j.1748-1716.1956.tb01312.x

1365-201X

B. C. R. Strömblad,

Amino Acid Enzymes and Metabolism

Summary. 1. Amine oxidase was demonstrated in the submaxillary and parotid glands of the cat. 2. Section of chorda tympani induces a fall in amine oxidase in the submaxillary gland. Postganglionic, but not preganglionic, parasympathetic denervation of the parotid gland causes decreased amine oxidase activity in the gland. 3. Excision of the superior cervical ganglion causes no fall in amine oxidase activity in salivary glands; in the parotid gland there is even an increased enzymic activity. 4. All types of denervation mentioned cause a supersensitivity to adrenaline and noradrenaline in the glands. The relation between amine oxidase decrease and supersensitivity after denervation is discussed. This work was supported by a grant from the Faculty of Medicine in Lund. Technical assistance was given by Miss Asta Hector.