Adherence in the Treatment of Psoriasis: A Systematic Review
2011; Karger Publishers; Volume: 222; Issue: 4 Linguagem: Inglês
10.1159/000329026
ISSN1421-9832
AutoresMatthias Augustin, Bart Holland, Dorothee C. Dartsch, Anna Langenbruch, Marc Alexander Radtke,
Tópico(s)Pharmaceutical studies and practices
Resumo<i>Background:</i> Medication adherence and compliance are essential for disease management and can significantly improve outcomes and quality of patient care. The literature suggests that up to 40% of patients do not use their medication as intended. <i>Objective:</i> To elucidate current knowledge on adherence/compliance in psoriasis. In particular, methods of adherence/compliance evaluation and influencing factors were to be identified. <i>Methods:</i> Systematic literature review based on a protocol-rooted search in online databases, followed by a structured critical appraisal and consecutive descriptive report. <i>Results:</i> Thirty-five original publications on adherence/compliance in psoriasis were identified, addressing the extent and quality of adherence/compliance in topical, systemic and UV treatments. Estimates of compliance varied considerably between 27 and 97%. Age, sex, psychosocial, disease-specific and treatment-specific factors were identified as predictors of adherence/compliance. <i>Conclusion:</i> A better understanding of the determinants of adherence can improve the outcomes of psoriasis treatment and lead to higher patient satisfaction and quality of care.
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