Initial experience with 99m Tc-hexamethyl-propylene amine oxime (HM-PAO) single photon emission computedtomography (SPECT) in patients with focal epilepsy
1987; Elsevier BV; Volume: 1; Issue: 2 Linguagem: Inglês
10.1016/0920-1211(87)90019-2
ISSN1872-6844
AutoresHermann Stefan, C. Kuhnen, H.-J. Biersack, K. Reichmann,
Tópico(s)Radiopharmaceutical Chemistry and Applications
ResumoBrain single photon emission computed tomography (SPECT) was performed in 16 patients with focal epilepsy, as well as EEG, using 99m Tc-HM-PAO SPECT and a rotating gamma camera system. Pathological Tc-HM-PAO SPECT findings were registered in 75%. CT was positive in 25%. MRI was positive in 76%. The results of Tc-HM-PAO SPECT findings were compared with those of CT and MRI. 61% of the MRI findings correlated with the pathological SPECT findings with respect to the side of the hemisphere, and in 75% of the patients the focal EEG abnormality and the pathological Tc-HM-PAO-SPECT findings were localized in the same hemisphere.
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