Influence of Drugs on Thyroid Function in Dogs
2003; Wiley; Volume: 17; Issue: 4 Linguagem: Inglês
10.1111/j.1939-1676.2003.tb02467.x
ISSN1939-1676
AutoresSylvie Daminet, Duncan C. Ferguson,
Tópico(s)Growth Hormone and Insulin-like Growth Factors
ResumoJournal of Veterinary Internal MedicineVolume 17, Issue 4 p. 463-472 Open Access Influence of Drugs on Thyroid Function in Dogs Sylvie Daminet, Sylvie Daminet Department of Small Animal Medicine, Ghent University, Belgium DMV, MSc, DACVIM, DECVIM-ca, Department of Small Animal Medicine, Ghent University, Salisbury-laan 133, B-9820 Merelbeke, Belgium; E-mail: sylvie.daminet@rug. ac.beSearch for more papers by this authorDuncan C. Ferguson, Duncan C. Ferguson Department of Physiology and Pharmacology, The University of Georgia College of Veterinary Medicine, Athens, GASearch for more papers by this author Sylvie Daminet, Sylvie Daminet Department of Small Animal Medicine, Ghent University, Belgium DMV, MSc, DACVIM, DECVIM-ca, Department of Small Animal Medicine, Ghent University, Salisbury-laan 133, B-9820 Merelbeke, Belgium; E-mail: sylvie.daminet@rug. ac.beSearch for more papers by this authorDuncan C. Ferguson, Duncan C. Ferguson Department of Physiology and Pharmacology, The University of Georgia College of Veterinary Medicine, Athens, GASearch for more papers by this author First published: 28 June 2008 https://doi.org/10.1111/j.1939-1676.2003.tb02467.xCitations: 97 AboutPDF ToolsRequest permissionExport citationAdd to favoritesTrack citation ShareShare Give accessShare full text accessShare full-text accessPlease review our Terms and Conditions of Use and check box below to share full-text version of article.I have read and accept the Wiley Online Library Terms and Conditions of UseShareable LinkUse the link below to share a full-text version of this article with your friends and colleagues. Learn more.Copy URL Share a linkShare onEmailFacebookTwitterLinkedInRedditWechat Abstract Several drugs can affect thyroid function test results in humans and eventually lead to an erroneous evaluation of thyroid function. These medications can alter the synthesis, secretion, transport, or metabolism of thyroid hormones. Some drugs also directly inhibit the hypothalamic-pituitary-thyroid axis. The effects of drugs on thyroid function in dogs have long been underestimated and have most likely contributed to the overdiagnosis of hypothyroidism in this species. This manuscript 1st reviews pertinent thyroid physiology followed by an overview of drugs for which the effects on canine thyroid function have been studied. The effects of glucocorticoids, propranolol, sulfonamides, phenobarbital, potassium bromide, and nonsteroidal anti-inflammatory agents (NSAIDs) on canine thyroid function are summarized here. Knowledge of the potential effect of these medications on thyroid function should contribute to a more reliable interpretation of thyroid function test results in dogs. References 1 Peterson ME, Melián C., Nichols R. 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