Carbon‐13 NMR spectra of methylated cyclobutanes and ethyl cyclobutane‐carboxylates
1980; Wiley; Volume: 13; Issue: 3 Linguagem: Inglês
10.1002/mrc.1270130308
ISSN0030-4921
AutoresErnest L. Eliel, K. Michał Pietrusiewicz,
Tópico(s)Computational Drug Discovery Methods
ResumoAbstract The 13 C NMR spectra of cyclobutane and seven methylated homologs and of ethyl cyclobutanecarboxylate and five isomeric diethyl cyclobutanedicarboxylates are reported and substituent parameters for methyl groups in methylcyclobutanes are calculated. Of note is a sizeable and nearly configuration‐independent upfield shifting γ‐effect.
Referência(s)